Factors that can produce gene mutations
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Mutations. Factors that can produce gene mutations…. Mutation : a change in the DNA sequence that is inherited. a) ____________ b) ______________ c) ______________. What happened?. What happened?.

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Factors that can produce gene mutations

Mutations

Factors that can produce gene mutations…

Mutation: a change in the DNA sequence that is inherited

a) ____________

b) ______________

c) ______________


What happened?

What happened?


____________ mutation: A mutation that causes the reading frame of codons to change, usually resulting in different amino acids being incorporated into the polypeptide


_________ mutation: A mutation at a specific base pair in the genome


_______________mutation: A mutation that converts a codon from an amino acid into a termination codon – very harmful!


_______________mutation: A mutation that results in the single substitution of one amino acid in the resulting polypeptide


Which one is worse missense or nonsense
Which one is worse, missense or nonsense?

A _________________ mutation results in the termination of the translation, therefore the protein is inactive.

A _________________ mutation can be just as harmful, however, there is the slight chance that it would not.


  • AUG UUU UUG CCU UAU CAU CGU

  • AUG UUU UUG CCU UAC CAU CGU


  • AUG UUU UUG CCU UAA CAU CGU

    • c) AUG UUU UUG CCU UAU CAU CGU

  • AUG UUU CUU GCC UUA UCA UCG U


  • Key differences in genome

    Prokaryotes harmful. Translate the mRNA sequence into protein to help you decide. The mutation is indicated in

    _______and circular

    All regions are coding, except for ________and __________

    ___________of operons

    Eukaryotes

    _______ and arranged in chromosomes

    Consists of coding and noncoding regions

    ___________of operons

    Key Differences in Genome


    Key differences in transcription

    Prokaryotes harmful. Translate the mRNA sequence into protein to help you decide. The mutation is indicated in

    Coupled with ___________

    Lack of ________means no excission

    Eukaryotes

    Occurs in the __________

    Introns excised by ______________ and exons joined together

    Key Differences in Transcription


    Key differences in translation

    Prokaryotes harmful. Translate the mRNA sequence into protein to help you decide. The mutation is indicated in

    Commence with _______-methionine

    Ribosome recognizes Shine-Dalarno sequence on mRNA as binding site

    Ribosomesare _________than in eukaryotes

    Eukaryotes

    Commences with methionine

    Ribosome recognizes 5’ cap on mRNA as binding site

    Occurs in the cytoplasm

    Ribosomes are larger than in prokaryotes

    Key Differences in Translation


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