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Reporting on Scientific Journal Articles

Reporting on Scientific Journal Articles. Jeremy Moore, M.A. Senior Manager, Science Communications American Association for Cancer Research jeremy.moore@aacr.org. Why is Cancer Newsworthy?. Why is Cancer Newsworthy?. Number 1 cause of death, surpassing heart disease in 2010.

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Reporting on Scientific Journal Articles

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  1. Reporting on Scientific Journal Articles Jeremy Moore, M.A. Senior Manager, Science Communications American Association for Cancer Research jeremy.moore@aacr.org

  2. Why is Cancer Newsworthy?

  3. Why is Cancer Newsworthy? Number 1 cause of death, surpassing heart disease in 2010

  4. Why is Cancer Newsworthy? Number 1 cause of death, surpassing heart disease in 2010 In the United States, it affects one in three women and one in two men

  5. Why is Cancer Newsworthy? Number 1 cause of death, surpassing heart disease in 2010 In the United States, it affects one in three women and one in two men Consequences both biological and psychological

  6. Why is Cancer Newsworthy? Money

  7. Why is Cancer Newsworthy? • Money • Government Money • NCI Budget, 2009: $4.96 billion • NCI Budget, 2010: $5.1 billion

  8. Why is Cancer Newsworthy? • Money • Government Money • NCI Budget, 2009: $4.96 billion • NCI Budget, 2010: $5.1 billion Budget Request for 2011 $5.26 Billion

  9. Why is Cancer Newsworthy? Money Private Money

  10. Why is Cancer Newsworthy? Money Private Money Corporate and Philanthropic

  11. Scientific Inquiry “In fact I have not failed 1,000 times. I have successfully discovered 1,000 ways not to make a light bulb.” --Thomas Edison

  12. Scientific Inquiry Cancer

  13. Scientific Inquiry • Cancer • Out of control cell growth

  14. Scientific Inquiry • Cancer • Out of control cell growth • More than 200 diseases

  15. Cancer CURE?

  16. Cancer CURE vs. CONTROL

  17. Cancer: The Scientific Questions Diagnosis

  18. Diagnosis • Bladder Cancer • Pancreatic Cancer • Ovarian Cancer • Breast Cancer • Colon Cancer • Skin Cancer

  19. Cancer: The Scientific Questions Diagnosis Screening

  20. Screening Questions surrounding PSA, Mammography, Colonoscopy

  21. Sensitivity vs. Specificity Sensitivity Specificity Correctly Identifying Who Is Not Sick • Correctly Identifying Who Is Sick

  22. MicroRNA “The discovery of MicroRNA can be equated with the idea that we’ve known for years that cars existed and only recently discovered they have a transmission. It’s that fundamental.” Philip Sharp, Ph.D., Nobel Laureate from M.I.T.

  23. MicroRNA News from Annual Meeting 2010 miR-21 and miR-106a are associated with an overall poor prognosis and that overexpressions of miR-181b and miR-203 are associated with poor outcomes in blacks for colorectal cancer MicroRNA-31 (miR-31) repressed specific tumor suppressors and, therefore, may be a novel pharmacologic target for lung cancer therapy and chemoprevention.

  24. MicroRNA News from Annual Meeting 2010 High levels of miR-21 were significantly correlated with poor response to Herceptin.

  25. DNA Methylation Levels

  26. Cancer: The Scientific Questions Diagnosis Screening Personalized Medicine

  27. Personalized Medicine

  28. Cancer: The Scientific Questions Diagnosis Screening Personalized Medicine Prevention

  29. Prevention “At least half of all cancer deaths are preventable by what we already know about healthy eating, exercise, maintaining appropriate weight, avoiding smoking and going for regular screenings.” Ernest T. Hawk, M.D., M.P.H. Vice President of the Division of Cancer Prevention and Population Sciences at The University of Texas M. D. Anderson Cancer Center.

  30. Prevention • Healthy Living

  31. Prevention Healthy Living Chemoprevention

  32. Prevention

  33. Scientific Inquiry 75 Clinical Trials & 11 Systematic Reviews Are Being Published Every Single Day Bastian H, Glaszio P, Chalmers I, et al. (2010). Seventy-Five Trials and Eleven Systematic Reviews a Day: How Will We Ever Keep Up? PLOS Med 7 (9): e1000326. doi:10.1371/journal.pmed.1000326.

  34. Journals to Watch New England Journal of Medicine

  35. Journals to Watch New England Journal of Medicine Journal of the American Medical Association

  36. Journals to Watch New England Journal of Medicine Journal of the American Medical Association Cancer

  37. Journals to Watch New England Journal of Medicine Journal of the American Medical Association Cancer Journal of Clinical Oncology

  38. Journals to Watch Cancer Research

  39. Journals to Watch Cancer Research Clinical Cancer Research

  40. Journals to Watch Cancer Research Clinical Cancer Research Cancer Epidemiology, Biomarkers & Prevention

  41. Journals to Watch Cancer Research Clinical Cancer Research Cancer Epidemiology, Biomarkers & Prevention Cancer Prevention Research

  42. Journals to Watch Cancer Research Clinical Cancer Research Cancer Epidemiology, Biomarkers & Prevention Cancer Prevention Research Molecular Cancer Research Molecular Cancer Therapeutics

  43. NEWS FLASH CANCER DISCOVERY

  44. NEWS FLASH • CANCER DISCOVERY • Officially announcing next week

  45. NEWS FLASH • CANCER DISCOVERY • Officially announcing next week • Editors in Chief, Jose Baselga, M.D, Ph.D. and Lewis Cantley, Ph.D.

  46. NEWS FLASH • CANCER DISCOVERY • Officially announcing next week • Editors in Chief, Jose Baselga, M.D., Ph.D., and Lewis Cantley, Ph.D. • Will be the premier venue for the publication and broad dissemination of high impact research in all areas of cancer research

  47. NEWS FLASH • CANCER DISCOVERY • Officially announcing next week • Editors in Chief, Jose Baselga, M.D., Ph.D., and Lewis Cantley, Ph.D. • Will be the premier venue for the publication and broad dissemination of high-impact research in all areas of cancer research. • First papers will be published online April 2011

  48. NEWS FLASH • CANCER DISCOVERY • Officially announcing next week • Editors in Chief, Jose Baselga, M.D., Ph.D., and Lewis Cantley, Ph.D. • Will be the premier venue for the publication and broad dissemination of high-impact research in all areas of cancer research • First papers will be published online April 2011 • In Print July 2011

  49. THE ANATOMY OF AN ABSTRACT Conclusions, not titles

  50. THE ANATOMY OF AN ABSTRACT Conclusions, not titles Goals

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