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NIH Mentored Career Development Awards (K Series) Part 2

NIH Mentored Career Development Awards (K Series) Part 2. Thomas Mitchell, MPH Department of Epidemiology & Biostatistics University of California San Francisco. Writing a competitive mentored K award grant application. Main sections of the grant application The Candidate (Sections 2 – 5)

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NIH Mentored Career Development Awards (K Series) Part 2

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  1. NIH Mentored Career Development Awards (K Series) Part 2 Thomas Mitchell, MPH Department of Epidemiology & Biostatistics University of California San Francisco

  2. Writing a competitive mentored K award grant application • Main sections of the grant application • The Candidate (Sections 2 – 5) • Statements by Mentors, Co-Mentors, and Collaborators (Section 7; limited to 6 pages) • Description of Institutional Environment (Section 8; limited to 1 page) • Institutional Commitment to Candidate’s Research Career Development (Section 9: limited to 1 page) • Research Plan (Sections 10 and 11)

  3. Statements by Mentors, Co-Mentors, and Collaborators • Assemble a complementary team • Choose a primary mentor who is a senior investigator with a track-record of NIH funding; your primary mentor should be at UCSF. • Include co-mentors who will complement the primary mentor’s strengths. • Avoid including co-mentors from institutions outside the Bay Area.

  4. Statements by Mentors, Co-Mentors, and Collaborators (Cont’d) • Each member of your “team” must play a role in your training or research plan. • Establish a relatively small (3-4) mentoring committee. • If you need to add additional members, call them scientific or technical advisors/collaborators, who have a relatively narrow area of responsibility and focus. • This section is limited to 6 pages. • Each member of your team must submit a signed letter. • The primary mentor’s letter should be at least 2 pages, leaving only 4 pages for all other members; hence, the total number of mentors/advisors on your team should not exceed 5.

  5. Statements by Mentors, Co-Mentors, and Collaborators (Cont’d) • Evaluation criteria for primary mentor: • Appropriateness of mentor’s research qualifications in the area of this application. • Quality and extent of mentor’s role in providing guidance and advice to candidate. • Previous experience in fostering the development of more junior researchers. • History of productivity and support. • Adequacy of support for the research project.

  6. Letters of Collaboration • The letter from the primary mentor is key. It should cover the following areas: • His or her qualifications in the research area proposed by the candidate. • Previous experience as a research supervisor. • The nature and extent of supervision that will occur during the award period. • Include an evaluation component that describes how your mentors will assess your progress (e.g., quarterly meetings). • Include specific milestones during the K award (e.g.,completion of coursework, submission of manuscripts). • What resources, if any, they will make available to you in support of your training and/or research. • See Example 1.

  7. Letters of Collaboration(cont’d) • Any of the following issues could also be addressed, which are the criteria by which the candidate will be evaluated: • Potential for conducting research • Evidence of originality • Adequacy of scientific background • Quality of research endeavors or publications to date • Commitment to patient-oriented research • Need for further research experience and training

  8. Primary mentor’s letter(cont’d) • The primary mentor’s letter can also “re-frame” any potential weaknesses in the application. • Examples: • Productivity of candidate (e.g., few publications). • Feasibility of conducting research plan with resources of K award. • Limited mentoring experience of primary mentor. • Limited resources of primary mentor (e.g., no current R01 funding. • Co-mentor(s) not at UCSF. • Scientific overlap with primary mentor.

  9. Letters of Collaboration(cont’d) • Letters from co-mentors, scientific advisors, and others can be much shorter. • Be sure to include description of the role of the co-mentor/scientific advisor. • Make sure that letters are consistent with text in grant application (re: frequency of meetings, etc.). • See Example 2.

  10. Description of Institutional Environment • This section is limited to 1 page. • Evaluation criteria: • Adequacy of research facilities and the availability of appropriate educational opportunities. • Quality and relevance of the environment for scientific and professional development of the candidate.

  11. Description of Institutional Environment (Cont’d) • Describe the research facilities and educational opportunities of the sponsoring institution (UCSF) that are related to the candidate’s career development training and research plans. • Include relevance of each component to your career development plan. • Describe resources outside UCSF, as needed. • See Example 3 .

  12. Institutional Commitment to Candidate’s Research Career Development • This section is limited to 1 page. • Evaluation criteria • Applicant institution’s commitment to the scientific development of the candidate and assurances that the institution intends the candidate to be “an integral part of its research program.” • Applicant institution’s commitment to protect at least 75% of the candidate’s effort for proposed career development activities.

  13. Institutional Commitment to Candidate’s Research Career Development (Cont’d) • These assurances are stated in a letter from your department chair or division chief (see Example 4). • Note: For fellows, this letter must state that you will be promoted from your current position to a “higher” position (ideally, to a full-time faculty position) during the K award period.

  14. Letters of Recommendation • 3 - 5 letters are required. • They should be from senior investigators who have competed successfully for NIH funding and have been involved in the training of junior investigators. • Can be from any period in your career (e.g., medical school, residency). • Cannot be from your primary mentor or co-mentors.

  15. Letters of Recommendation(cont’d) • Letters should address the candidate’s potential for a research career. • Potential for conducting research • Evidence of originality • Adequacy of scientific background • Quality of research endeavors or publications to date • Commitment to patient-oriented research • Need for further research experience and training

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