WHAT ARE MESENCHYMAL STEM CELLS (MSC) ?. First isolated by Friedenstein et al in 1974Fibroblastoid cells - spindle-shapedAdherent to tissue culture glass or plasticHigh growth potential. WHY ARE MSC INTERESTING ?. Rat MSC genetically tagged are microinjected into a mouse blastocyteBlastocyte reimplanted into another ratBlastocyte allowed to develop into baby rat -> sacrificedGene tags are found in many of the baby rat tissues tested ->Embryonic stem cells?.
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