Infections of ruminants

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Viral infections of the respiratory tract. BRSV IBR ParainfluenzaBVDVAdenovirusesMaedi-Visna. Infectious Bovine Rhinotracheitis - IBR. Acute disease of upper resp. tractFever, keratoconjunctivitis, nasal and occular discharge, explosive cough, salivationNon-complicated disease lasts 10-14 da

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Infections of ruminants

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1. Infections of ruminants

2. Viral infections of the respiratory tract BRSV IBR Parainfluenza BVDV Adenoviruses Maedi-Visna

3. Infectious Bovine Rhinotracheitis - IBR Acute disease of upper resp. tract Fever, keratoconjunctivitis, nasal and occular discharge, explosive cough, salivation Non-complicated disease lasts 10-14 days Frequent secondary infections (Pasteurella)

4. IBR - diagnostics Izolation on TC Typization by monoclonal antibodies Seroconversion (dynamique)

5. BRSV Main pathogen in the respiratory complex Affects young age category High incidence of the disease, mortality up to 20% (bacterial coinfections) Biphasic disease curve Colostral antibodies doesn´t protect against infection

6. BRSV - diagnostics Very labile virus, izolation on TC not reliable Antigen capture ELISA IF test Detection of VN antibodies (paired samples) Calf with colostral antibodies doesn´t seroconvert

7. THE RESPIRATORY TRACT

8. THE RESPIRATORY TRACT

9. Infection of GIT BVDV Bovine Coronavirus Bovine Rotavirus Some serotypes of adenoviruses

10. Coronavirus skotu Primary pathogen Disease of 3-21 day old calf, sometimes in older animals (up to 3 months) Watery diarrhoea, dehydratation, acidosis… Virus replication in distant part of the gut, desquamation, malabsorption syndrome Enzootic disease, prevalence up to 100%

11. Bovine Coronavirus - diagnostics Virus shedding stops after exfoliation of infected enterocytes IF detection smears Sections of the gut Antigen capture ELISA Immunoelectron microscopy Isolation on TC (some strains only, long lasting) HA test

12. Bovine Coronavirus - diagnostics Detection of antibodies Ab are virtually in all animals Dynamics of seroconversion (IgM or IgA)

13. Bovine Rotavirus Primary pathogen, endemic Calfs -1-2 weeks (then subclinical course) Diarrhoea Milder course than in coronaviruses, same pathogenesis At least 3 serotypes No cross protection

14. Bovine Rotavirus - diagnostics IEM IF test Cell line MA104 – IF confirmation ELISA kits Latex agglutination test Antibody detection- high serological prevalence

15. THE ALIMENTARY TRACT actinobacilosis (soft tissues infection)  Actinobacillus lignieresii benzylpenicillin i.v.,i.m.   actinomycosis (bone infection)  Actinomyces bovis benzylpenicillin i.m.

16. THE ALIMENTARY TRACT enteritis/enterotoxicosis/enterotoxemia E. coli (F5) calves less than 1 w. colistin p.o inact. vac. s.c. Salmonella Enteritidis, S. Typhimurium calves 1-5 w enrofloxacin p.o.  C. perfringens typ A,C calves tylosin i.m. inact. vac. s.c.  Salmonella Typhimurium feed lot enrofloxacin i.m., p.o.  Salmonella Dublin cephalosporines 1.-3.g i.v.,i.m.

17. Infection of genital tract IBR BVDV Scrapie

18. THE URINARY TRACT

19. THE REPRODUCTIVE SYSTEM

20. THE REPRODUCTIVE SYSTEM

21. MAMMARY GLAND - MASTITIS

22. Infection of CNS Maedi-Visna CAEV IBR BVDV BSE Scrapie

23. THE CENTRAL NERVOUS SYSTEM

24. THE EYE

25. Skin Infections Bovine Papillomavirus Bovine poxvirus Ovine poxvirus Herpesvirus - mamilitis

26. THE SKIN

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