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2. NIH Institutes and Centers (ICs)
4. Research Training & Career Timetable
5. NRSA Fellowships (F) & Training (T) Grants
6. NRSA Eligibility and Regulations Must be Citizen, non-citizen national, or lawfully admitted for permanent residence.
NRSA Fellows: Individual Fellowships (F)
NRSA Trainees: Institutional Training (T) Grants.
Predoctoral Fellows and Trainees: Must have a baccalaureate degree & be enrolled in doctoral program leading to Ph.D., comparable research doctoral degree or dual research/clinical doctorate like the M.D./Ph.D.
Postdoctoral Fellows and Trainees: Must have a Ph.D. or M.D. or comparable doctoral degree from an accredited domestic or foreign institution.
Duration of Support: 5 years (Predoc) and 3 Years (Postdoc) in aggregate.
7. Individual NRSA Fellowships: Overview Individual Fellow applies through University/Institution.
Up to 5 years (Predoctoral) and 3 years (Postdoctoral) of support; service payback obligation for Postdoctoral Fellows and Trainees.
Research & training plans; potential to become an independent investigator.
Annual progress reports
Stipend: Not salary; subsistence allowance to help defray living expenses.
Fellow not an employees of either Government or University.
8. Individual NRSA Fellowships: Mechanisms F30: Individual predoctoral fellowship for MD/PhD or other dual-degree training. Applicants must show potential to become productive, independent physician-scientists.
F31: Individual predoctoral fellowship. Provide support for promising doctoral candidates (dissertation phase) in research fields relevant to the missions of the NIH.
F31: Individual predoctoral fellowship to promote diversity in research. Provide support for training leading to the PhD or MD/PhD degree (or equivalent).
F32: Individual postdoctoral fellowship. Provide support to applicants with potential to become productive, independent research investigators.
F33: Individual senior fellowship. Provide support to experienced scientists who wish change research direction or broaden their research capabilities.
9. NRSA Stipends: FY 2008
10. Tuition and Health Insurance: Policy
11. Funded NRSA & Non-NRSA Training Grants & Fellowships
12. Pre- and Postdoctoral Positions on NRSA Training Grants and Fellowships: FY 2007
13. Success Rate of NRSA Predcotoral Fellowship (F31) Applications
14. Suucees Rate of NRSA Postdoctoral Fellowship (F32) Applications
15. Success Rate of NRSA Training Grant (T32) Applications
16. Research Career Development Awards
17. Common Features: Eligibility Read Program Announcements carefully and contact NIH staff.
Research doctoral degree (K01, K02), but some require clinical doctoral degree (K08, K23).
US Citizens, Non-Citizen Nationals, Permanent Residents (except K99/R00).
Previous NIH Principal Investigators may be Ineligible
Usually Principal Investigator on R03 or R21 is OK (except K99/R00).
Principal Investigator on R01 or subproject Principal Investigators on a P01 is not OK.
18. Three, Four, or Five years depending on mechanism and justification of need.
Extensions in time – award terms remain in effect (i.e. minimum effort, no salary from other federal funding source).
Entry level awards require a mentor, multiple mentors are encouraged.
Mentored K awardees are encouraged to apply for independent support during the K award. Common Features: Duration
19. Common Features: Effort At least 75% effort committed to research and the rest on other career development activities.
Policy: Awardee must have a full-time appointment (12 person months) at applicant institution, and the minimum effort requirement must be covered by that appointment.
Policy Update: Mentored K awardees in final 2 years may reduce effort (to minimum of 50%) on K if replaced by effort as Principal Investigator on research project or subproject of Center grant, provided they remain in mentored situation.
Temporary reduction permissible in unusual and pressing circumstances.
20. Vary across NIH Institutes and Centers, so read specific announcements carefully and contact NIH staff.
Salaries capped between $75,000 and legislated cap ($191,300 for FY 2008).
Fringe benefits are in addition to any cap, plus 8% F&A costs.
Salary supplementation OK, but must be from non-Federal sources and must not require extra duties that would interfere with K activities.
Research costs: Generally $25,000 to $50,000 and commonly used for supplies, equipment, technical personnel, travel to research meetings or training, tuition/fees, computational services.
Ancillary personnel support is not allowed, such as salary for administrative/secretarial support, support for mentors. Common Features: Costs
21. K01: Mentored Research Scientist Development Award.
K08: Mentored Clinical Scientist Development Award.
K23: Mentored Patient-Oriented Research Development Award.
K25: Mentored Quantitative Research Development Award.
K99/R00: NIH Pathway to Independence (PI) Award.
K02: Independent Scientist Award.
K24: Mid-Career Patient-Oriented Research Development Award.
K12: Institutional Mentored Research Scientist Development Program. Mentored Career Awards: Which One?
22. Total Competing Dollars Awarded to Research Career (K) Awards
23. Numbers of Entry Level Research Career (K) Awards
24. NIH Success Rates for Selected K Awards Fiscal Years 1997-2006
25. Pathways to Independence Award (K99/R00): facilitate receiving an R01 award earlier in an investigator's research career.
NIH Director's New Innovator Award.
NRSA Individual and Institutional Training Awards.
Career Development Awards.
Research Project Grants.
Institute and Center Practices.
Resources for New Investigators.
NIH Loan Repayment Programs.
26. NIH New Investigator Policy Goal is to encourage funding for scientists new to NIH and those who are at an early stage in their careers.
New investigators are considered essential to the vitality of health-related research, thus several NIH initiatives to nurture promising scientists.
New policy intended to level the playing field to allow new investigators to achieve success rates comparable to those of established scientists.
Early Stage Investigator (ESI): New or First-time investigator within 10 yrs of completing last research degree or within 10 yrs of completing medical residency.
The ESI policy is an important part of NIH initiative to enhance the peer review process with a goal to “fund the best science, by the best scientists, with the least amount of administrative burden.”
27. New Investigators receive special attention at Council as high program priority or equivalent.
Increased payline for scored R01 applications from New Investigators.
No imposed reductions in duration and amount of awards (beyond the recommendations of the initial review group) for New Investigators.
Fund applications to achieve a designated success rate rather than setting a specific payline for New Investigators applying for R01s.
R01 New Investigators whose applications score below the payline can submit 5-page letters responding to critiques in the summary statement for Advisory Council review. If these letters respond satisfactorily to the concerns raised by the study sections, the Council can decide to fund these applications, avoiding the need for resubmission.
http://grants1.nih.gov/grants/new_investigators/index.htm
28. New Innovator Award (DP2): Purpose New Innovator awards are designed to support unusually creative new investigators with highly innovative research ideas at early stage of their career when they may lack preliminary data required for an R01 grant.
New Innovator award program complements ongoing efforts by NIH to fund new investigators through R01 grants.
Competition in FY09 will proceed in two phases: Pre-Application, evaluated by external reviewers, followed by Full Application.
Peer review emphasizes the potential of the project, if successful, to have a significant impact on an important biomedical or behavioral research problem.
29. New Innovator Award (DP2): Eligibility Applicants must hold an independent research position at a domestic institution, and received doctoral degree or completed internship/residency within past 10 years.
Definition of “new investigator” – Not awarded an R01 or equivalent NIH grant. Current/past mentored K awardees eligible.
Must commit at least 25% of research effort each year to activities supported by the New Innovator Award.
There are no citizenship or residency requirements.
Awards will be for up to $300,000 in direct costs each year for five years, plus applicable F&A costs. Up to 24 awards will be made in 2009.
30. NIH Loan Repayment Programs
31. Extramural Loan Repayment Programs
32. Benefits and Terms *Renewals: You can apply for a competitive renewal provided NIH’s eligibility requirements are continued to be met.
The LRPs will repay 50% of an individual’s qualified outstanding educational debt up to $35,000 per year. NIH issues quarterly payments directly to the lenders to repay principal and interest
For a two-year research commitment that could mean as much as $70,000 in loan repayments.
Additional example: Individual has $140,000 in qualified student loan debt. They qualify for $35,000/year repayment because it is not more than 50% of their outstanding educational debt. After two years of loan repayments, their debt is reduced by $70,000 to $70,000 remaining. If they successfully renew, the most they could get per year on the next contract is $17,500 (x2 years = $35,000, which is 50% of their outstanding educational debt). Total educational debt reduced by $105,000 after 4 years.
Since loan repayments are considered to be income by the IRS, an amount equal to 39% of your LRP loan repayments will be provided to offset the additional tax burden. The tax payments are not sent to the participant but to the IRS directly
LRP awards are portable and can be transferred, subject to NIH approval of qualifying nonprofit environment and research project
New LRP contracts are awarded for two years. Provided they continue to meet eligibility requirements, including debt levels, participants may submit a renewal application. Renewals contracts are awarded for one or two years, after which the participant can renew again, provided they remain eligible.
*Renewals: You can apply for a competitive renewal provided NIH’s eligibility requirements are continued to be met.
The LRPs will repay 50% of an individual’s qualified outstanding educational debt up to $35,000 per year. NIH issues quarterly payments directly to the lenders to repay principal and interest
For a two-year research commitment that could mean as much as $70,000 in loan repayments.
Additional example: Individual has $140,000 in qualified student loan debt. They qualify for $35,000/year repayment because it is not more than 50% of their outstanding educational debt. After two years of loan repayments, their debt is reduced by $70,000 to $70,000 remaining. If they successfully renew, the most they could get per year on the next contract is $17,500 (x2 years = $35,000, which is 50% of their outstanding educational debt). Total educational debt reduced by $105,000 after 4 years.
Since loan repayments are considered to be income by the IRS, an amount equal to 39% of your LRP loan repayments will be provided to offset the additional tax burden. The tax payments are not sent to the participant but to the IRS directly
LRP awards are portable and can be transferred, subject to NIH approval of qualifying nonprofit environment and research project
New LRP contracts are awarded for two years. Provided they continue to meet eligibility requirements, including debt levels, participants may submit a renewal application. Renewals contracts are awarded for one or two years, after which the participant can renew again, provided they remain eligible.
33. Eligibility *Contraception and Infertility Research LRP is available to those with doctoral level degree, as well as nurses, physician assistants, graduate students, and postgraduate research fellows training in the health professions.
†Individuals with a DVM degree are not eligible for the Clinical Research LRPs.
Generally, LRP applicants must hold a doctoral level degree (Ph.D., M.D. or equivalent). One exception: the Contraception and Infertility Research LRP is available to nurses, physician assistants, graduate students, and postgraduate research fellows training in the health professions, as well.
As long as you receive your qualifying degree before the contract date, July 1 you may apply for the LRP. You will be required to submit a letter from your school verifying that you will defend your dissertation and receive your degree by the contract date
Qualifying educational debt—including undergraduate, graduate, and medical school loans—must be at least 20% of the applicant’s annual base salary. For example, an individual making $50,000, would need at least $10,000 of educational debt to be eligible.
Research may be conducted on a full or part-time basis. Qualifying research must be conducted for an average of 20 hours per week during each contract quarter. Research activities must be verified by the participant’s supervisor.
The research must be funded by a domestic (U.S.-based) nonprofit entity. Research activities may be conducted abroad, as long as this requirement is satisfied.
NIH grant or other award support is not required to participate in the LRPs.
*Contraception and Infertility Research LRP is available to those with doctoral level degree, as well as nurses, physician assistants, graduate students, and postgraduate research fellows training in the health professions.
†Individuals with a DVM degree are not eligible for the Clinical Research LRPs.
Generally, LRP applicants must hold a doctoral level degree (Ph.D., M.D. or equivalent). One exception: the Contraception and Infertility Research LRP is available to nurses, physician assistants, graduate students, and postgraduate research fellows training in the health professions, as well.
As long as you receive your qualifying degree before the contract date, July 1 you may apply for the LRP. You will be required to submit a letter from your school verifying that you will defend your dissertation and receive your degree by the contract date
Qualifying educational debt—including undergraduate, graduate, and medical school loans—must be at least 20% of the applicant’s annual base salary. For example, an individual making $50,000, would need at least $10,000 of educational debt to be eligible.
Research may be conducted on a full or part-time basis. Qualifying research must be conducted for an average of 20 hours per week during each contract quarter. Research activities must be verified by the participant’s supervisor.
The research must be funded by a domestic (U.S.-based) nonprofit entity. Research activities may be conducted abroad, as long as this requirement is satisfied.
NIH grant or other award support is not required to participate in the LRPs.
34. Online Information and Application The extramural LRP application cycle is open each year from September 1 through December 1.
LRP applications are completed online by visiting the Web site: www.lrp.nih.gov. Applications may be started and then saved and completed at another time.
The entire application is web based and our DLR information center is available to walk you through the application and answer your questions
Sign up on the Web site to receive e-mail alerts about the application cycle and other important LRP information.
The Web site is being redesigned and will soon include new resources to assist people in preparing sections of their application prior to the application cycle. The extramural LRP application cycle is open each year from September 1 through December 1.
LRP applications are completed online by visiting the Web site: www.lrp.nih.gov. Applications may be started and then saved and completed at another time.
The entire application is web based and our DLR information center is available to walk you through the application and answer your questions
Sign up on the Web site to receive e-mail alerts about the application cycle and other important LRP information.
The Web site is being redesigned and will soon include new resources to assist people in preparing sections of their application prior to the application cycle.
35. New Applications and Success Rates FY 2007
36. Renewal Applications and Success Rates FY 2007
37. Enhancing Peer Review at NIH (1 of 2) Overview: “Fund the best science, by the best scientists, with the least amount of administrative burden…” Dr. Elias Zerhouni, Director, NIH, June, 2007.
NIH has a long history of supporting the most promising and meritorious biomedical research. While peer review is a cornerstone of NIH, the increasing breadth, complexity, and interdisciplinary nature of modern research has created many challenges.
External and Internal working groups formed to assess challenges and make recommendations, in 3 phases:
38. Enhancing Peer Review at NIH (2 of 2) Diagnostic Phase: External & internal evaluation of peer review.
Design Implementation Plan:
Priority 1 – Engage the Best Reviewers: Excellence of peer review is directly correlated with the ability to recruit and retain the most accomplished, broad-thinking, and creative scientists.
Priority 2 – Quality & Transparency of Review: The peer review process must strive for maximum clarity, fairness, and consistency and help applicants determine a best course of action once reviewed. Focus on the potential impact, originality, and feasibility of the proposed research.
Priority 3 – Provide Balanced and Fair Reviews Across Scientific Fields and Career Stages: Peer review should fairly evaluate proposals from all scientists, regardless of career stage or discipline, avoid bias towards more conservative/proven approaches at expense of innovation and originality.
Priority 4 – Continuous Review of Peer Review: Develop a permanent process for continuous review of peer review.
Begin Implementation of Selected Actions: Peer Review Oversight Committee consisting of NIH program, review, grants management, and evaluation staff to assist with implementation plan for 2009-2010.
40. NIH Institutes and Centers: http://www.nih.gov/icd/
Grants and Funding Opportunities: http://grants1.nih.gov/grants/
Research Training Opportunities: http://grants1.nih.gov/training/index.htm
Forms and Applications: http://grants1.nih.gov/grants/forms.htm
Electronic Submission of Applications: http://era.nih.gov/ElectronicReceipt/
Grants Policy and Guidelines: http://grants1.nih.gov/grants/policy/policy.htm
NIH Guide for Grants and Contracts (the NIH Guide) http://www.nih.gov/grants/guide/index.html
