INTRODUCTION. I. Cell Biology. A. Definition. B. History of Cell Biology. 1. Microscope Development. a. Zacharias Janssen , 1595 first light microscope. b. Galileo , 1609 focusing device. c. Robert Hooke , 1665 coined “ Cellulae”.
B.History of Cell Biology
b. Galileo, 1609 focusing device
c. Robert Hooke, 1665 coined “Cellulae”
d. Anton VanLeeuwenhoek, 1672 “Homunculus” and “Animalcules”
f. Max Knot & Ernst Ruska, 1933 first electron microscope
b. Robert Brown, 1824 Brownian motion & thenucleus
c. Theodor Schwann & Matthias Schleiden, 1839 Cell Theory
i. The cell is the basic unit in living organisms.
ii. The cell is the building block of organisms.
e. Rudolph Virchow, 1859 “Spontaneous Generation”
iii. Cells arise from preexisting cells.
a. Karl VanNageli, 1846 plant cells derived from direct division of maternal cells
b. E. Strausburger & Walter Fleming, 1840’s directions for growth and division of cells contained in the nucleus
c. Gregor Mendel, 1860’s proposed a hereditary molecule was responsible for expression of traits in an organism
d. Frank Meischer, 1871 proposed nuclein material of nucleic acids
d. Robert Altmann, 1889 purified nucleic acids into purine and pyrimidine bases DNA in all cells, while RNA variable
e. James Watson & Francis Crick, 1953 summarized research and built model of DNA
A. Highly Organized
A. Size Limits
The parts == protein (capsid , landing gear, and injector) surrounding a nucleic acid core (genome= can be DNA or RNA)