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Conjunctival Lymphoma Masquerading a Chalazion in a Child

Conjunctival Lymphoma Masquerading a Chalazion in a Child. Michael Waisbourd, MD * Igal Leibovitch, MD* Dror Sayar , MD † Ronit Elhasid, MD † *Department of Ophthalmology † Pediatric Hemto -Oncology unit Tel Aviv Medical Center, Tel Aviv, Israel. Introduction.

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Conjunctival Lymphoma Masquerading a Chalazion in a Child

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  1. Conjunctival Lymphoma Masquerading a Chalazion in a Child Michael Waisbourd, MD* Igal Leibovitch, MD* DrorSayar, MD† Ronit Elhasid, MD† *Department of Ophthalmology †Pediatric Hemto-Oncology unit Tel Aviv Medical Center, Tel Aviv, Israel

  2. Introduction • Childhood conjunctival lymphoma is an extremely rare entity and may comprise a diagnostic challenge • We report a case of childhood conjunctival lymphoma masquerading as an internal chalazion.

  3. Case report • A 13-year-old girl was referred to our department with a three weeks history of right lower lid forniceal mass, initially diagnosed as a chalazion

  4. Case report • On examination, a 15 millimeter elevated pink conjunctival mass was apparent in her lower fornix. The mass was surgery excised. Figure 1

  5. Case report • Figure 2A. Groups of cells containing large nuclei with scarce cytoplasm (arrow) and nucleoli (arrowhead), positive for CD20 and Ki67 staining (2B, 2C). Figure 2

  6. Case report • Polymerase chain reaction analysis of the immunoglobulin heavy chain gene rearrangement showed monoclonality of B-cells. • The results were compatible with large B cell lymphoma.

  7. Conclusions • Although conjunctival lymphoma is a very rare entity in children, it should be included in the differential diagnosis of an eyelid or conjunctival mass

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