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UMUC-14

A. p=0.0111. ns. Ctrl Ab. R3Mab. Ctrl Ab. R3Mab. B. UMUC-14. SW780.

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UMUC-14

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  1. A p=0.0111 ns Ctrl Ab R3Mab Ctrl Ab R3Mab B UMUC-14 SW780 Supplemental Figure 8 Effect of R3Mab on serum levels of human pro-MMP-10 in mice bearing UMUC-14 or SW780 xenograft tumors. (A) Effect of R3Mab on the growth of pre-established SW780 xenograft tumors. (B) Effect of R3Mab on serum levels of human pro-MMP-10. Mice with pre-established tumors were grouped randomly into cohorts of 5 or 6 for treatment with either a control antibody (Ctrl Ab) or R3Mab (30 mg/kg). Serum was collected at 96 hr post-treatment, and human pro-MMP-10 level was measured by Elisa.

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