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Honors Biology Chapter 7

Honors Biology Chapter 7. Beyond Mendelian Genetics. Many Human Phenotypes Follow Mendelian Pattern. One gene / two alleles = 1 trait. Genetic Disorders Rare heritable illnesses . Most lethal disorders are recessive . Cystic Fibrosis. Huntington’s Disease – Dominant.

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Honors Biology Chapter 7

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  1. Honors Biology Chapter 7 Beyond Mendelian Genetics

  2. Many Human Phenotypes Follow Mendelian Pattern One gene / two alleles = 1 trait

  3. Genetic Disorders Rare heritable illnesses • Most lethal disorders are recessive

  4. Cystic Fibrosis

  5. Huntington’s Disease – Dominant

  6. Some Deleterious Genes Are Sex-Linked • X-linked Recessive • Hemophilia (Bleeders Disease)

  7. Hemophilia

  8. Hemophilia

  9. X-linked Dominant • Retinitis Pigmentosa

  10. Non-Mendelian GeneticsComplex Patterns of Inheritence • Traits do not segregate according to Mendel’s Laws • X inactivation • Incomplete Dominance • Codominance • Polygenic Traits • Epistasis • Multiple Alleles • Environmental Influences • Others

  11. X-Inactivation

  12. X-Inactivation

  13. Epistasis

  14. Incomplete Dominance

  15. Codominance

  16. Codominance

  17. Multiple Alelles

  18. Sex-linked Traits

  19. Polygenic Traits

  20. Polygenic Traits

  21. Polygenic Traits

  22. Polygenic Traits

  23. Gene Linkage

  24. KaryotypesPrepared from blood, bone marrow, amniotic fluid, placenta

  25. Karyotypes

  26. KaryotypesDetect Abnormal #

  27. KaryotypesDetect Structural Defects

  28. Pedigrees

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