Resveratrol. A Phytochemical With Health Benefits Found in Red Wine. Chem 11 Spring 2008. Resveratrol is a stilbene. Stilbene :. Resveratrol. Resveratrol. Health Benefits of Phytochemical s. Antoxidant activity Cancer inhibition Cholestrol regulation Anti-inflammatory activi ty.
A Phytochemical With Health Benefits Found in Red Wine
2O2 + NADPH 2O2- + NADP+ + H+
2O2- + 2H+ dismutase H2O2 + O2
H2O2 + O2- + H+ H2O + O2 + OH
Disruption of normal cell activities
The body uses the most dangerous free radicals for use in the immune system and in inflammatory reactions.Effects of Free Radicals
-C=C- + OH - C – C -
There may not be enough Resveratrol in a glass of wine to yield clinical benefits, but it’s like chicken soup …
A little bit won’t hurt you and it might do you some good.
National Cancer Institution. “Antioxidants and Cancer Prevention: Fact Sheet.” 2008 May 10. <http://www.cancer.gov/ cancertopics/factsheet/antioxidantsprevention>.
National Cancer Institution. “Red Wine and Cancer Prevention: Fact Sheet.” 2008 May 10. <http://www.cancer.gov/ cancertopics/factsheet/red-wine-and-cancer-prevention>.
“New Insights into the Mechanism of Action of Antioxidants.” 2008 May 10 <http://ods.od.nih.gov/news/conferences/ ada2002/Milner_ abstract.html>
Sharma, H. M.D., C. Clark, M.D. An excerpt from the medical textbook Contemporary Ayurveda. Edinburgh: Churchill Livingstone, 1998. 2008 May 10.<http://www.bsherman.org/freeradicals.htm>.
Silverthorn, Dee Unglaub. Human Physiology: An Integrated Approach. 4th ed. San Francisco: Pearson
Educaton Inc. 2007. 22
J Bauer, D Sinclair, “Therapeutic potential of Resvertrol: the in vivo evidence”, National Revue Drug Discovery, 2006, 5(6): 494 – 506
K Huwitz, D Sinclair, “Small molecule activatiors of sirtuins extend Saccharomycescerevisiae lifespan”, Nature, 2003 Sep 11:425 191 – 6
Ming-Tsan Lin, Men-Luh Yen, Chia-Yi Lin, and Min-Liang Kuo, “Inhibition of Vascular Endothelial Growth Factor-Induced Angiogenesis by Resveratrol through Interruption of Src-Dependent Vascular Endothelial Cadherin Tyrosine Phosphorylation”, Mol Pharmacol 2003, 64:1029-1036