1 / 16

RECURRENT MISCARRIAGE Dr.F Mardanian MD

RECURRENT MISCARRIAGE Dr.F Mardanian MD. CASE 35 Y G5L1Ab4 G1=L1 G2=16weeks G3=8weeks G4=12weeks G5=16weeks BW=105kg Vaginal Exam  Uterus>NL Sonography(TVS)= Uterus>NL Hysterosalpingography=NL Lab Data:

gjason
Download Presentation

RECURRENT MISCARRIAGE Dr.F Mardanian MD

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. RECURRENTMISCARRIAGEDr.FMardanian MD

  2. CASE • 35 Y G5L1Ab4 G1=L1 G2=16weeks G3=8weeks G4=12weeks G5=16weeks BW=105kg • Vaginal Exam  Uterus>NL • Sonography(TVS)= Uterus>NL • Hysterosalpingography=NL • Lab Data: • TSH=NL Prolactin=NL Anticardiolipin Ab=NL Lupus Anticoagulant Ab=NL GTT=NL ProteinC,S-AntithrombinIII=NL • Pathologic Findings=Chorionic Villosities • Parents Karyotype=NL

  3. ETIOLOGY • Genetics 3-5% Couples with Recurrent Miscarriage PGD/S • Anatomic • Immunologic • Thrombophilic • Endocrine • Infectious factors • Enviromental Factors • Unexplained 50% PGD/S

  4. PLAN

  5. What is the prognosis of subsequent pregnancy after 3times unexplained Abortion? 30-40% risk of repeated Abortion.

  6. When should we evaluate cause of recurrent Abortion? (After 2times Abortion) • Detected FHR in previous pregnancies. • Maternal age >35. • Infertility. • Normal karyotype of gestational tissue.

  7. What is the relationship between Gestational Age and cause of Abortion? • First Trimester=50% chromosomal abnormality. • Early Abortion=70% chromosomal abnormality.

  8. What is the relationship between Obesity and Recurrent Miscarriage? • Body Mass Index>=30 • Insuline Resistance.

  9. Is there any relationship between PCO and Recurrent Miscarrige? • 20-25% increased risk for first trimester Miscarriage. • Insuline Resistance.

  10. Infectious factors: Which Lab Data is necessary? • Cervical culture • Endometrial biopsy Specially for patiens with Cervicitis-Chronic Bacterial Vaginosis-PID

  11. What is the role of Cerclage in Recurrent Miscarriage? • History of second trimester Pregnancy Loss. • Increased Shortening of cervix in Pregnancy.

  12. What is the first choice Treatment in Thrombophilia? • HEPARIN

  13. What is the miscarriage rate in patients with ADENOMYOSIS? • 11% • Mechanism:Nitric Oxide.

  14. What is the Role of Pathology In Recurrent Miscarriage?

  15. THANK YOU…

More Related