Nutrition Expedition

1. Nutrition Expedition Presentation by: Sharina Wilson Biological Molecules and their functions Investigating the three of the four major biological molecules, including structure and function within biological systems.

2. What are Biological molecules?? Biological macromolecules are defined as large molecules made up of smaller organic molecules. There are four classes of macromolecules: carbohydrates, lipids, proteins and nucleic acids. Together, these elements make up almost all living things.

3. Carbohydrates: • Carbohydrates are an essential structural component of living cells and source of energy for animals; includes simple sugars with small molecules as well as macromolecular substances. They are sugars, starches, and cellulose, which contain CHO and which function primarily in energy storage, energy transport, and plant structure. A carbohydrate is an organic compound consisting only of carbon, hydrogen and oxygen. Carbohydrates can be viewed as hydrates of carbon, hence their name.

4. Lipids Lipids are an essential structural component in living cells in that they: help with cell membrane structure constitute a barrier for the cell control membrane fluidity control the flow of material that go in and out of the cell act as an energy storage (fats stored in adipose tissue) transmit information in cells can act as a Lipid Vitamin required for metabolism. Fats, oils and waxes are all examples of Lipids, which are molecules necessary for the survival of all living organisms. A lipid is composed of a glycerol, a type of alcohol, attached to three fatty acid chains composed of a carbon skeleton with attached hydrogen atoms.

5. Proteins Proteins play an important role in the lifespan and quality of human life. Depending on the roles, bonds and the structure of the amino acid, the proteins in the cell membrane play the role of: channels to facilitate diffusion and to transfer molecules according to electrical and chemical qualities and as transporters (they bind with glucose molecules to transport them to the other side of the membrane). organic catalysts in human anatomy They also go on to effect the world by being able to influence the nature of enzymes.

6. Dehydration Synthesis: • Large polymers are made in a process called dehydration synthesis.  They are constructed by linking small monomers (building blocks) together.  Each time two monomers are linked, a molecule of water must be removed.  • Dehydration refers to the removal of water and synthesis refers to the linking of the monomers together. Hydrolysis: • Small monomers are made in process called hydrolysis.  Basically, large polymers are broken back down into small monomers by the addition of water.  • Hydro stands for the addition of water and lysis means to break.

7. Monomers and Polymers: A monomer is a molecule that is able to bond in long chains. Polymer means many monomers (Poly means many). The Monomers and Polymers in Carbohydrates, Lipids and Proteins:

8. Structure: Carbohydrates Carbohydrates consist of the elements carbon (C), hydrogen (H) and oxygen (O) with a ratio of hydrogen twice that of carbon and oxygen. In their basic form, carbohydrates are simple sugars or monosaccharides. These simple sugars can combine with each other(Dyhydration Synthesis) to form more complex carbohydrates (ex: Glucose). Monosaccharides are Monomers. The combination of two simple sugars is a disaccharide (Ex: Sucrose). Disaccharides are Monomers. Those with a larger number are called polysaccharides (Ex: Amylose starch). Polysaccharides are known as a Polymer. Basically, a monosaccharide has just one ring, a disaccharide has two, and a polysaccharide has many.

9. Structure: Lipids Monoglyceride Fats and oils are made from two kinds of molecules: glycerol (a type of alcohol with a hydroxyl group on each of its three carbons) and three fatty acids joined by dehydration synthesis. A monoglyceride is a glyceride consisting of one fatty acid chain covalently bonded to a glycerol molecule through an ester (the bonding between fatty acids and glycerol that characterizes true fats) linkage. A diglyceride is a glyceride consisting of two fatty acid chains covalently bonded to a glycerol molecule through ester linkages. Mono- and diglycerides are commonly added to commercial food products in small quantities. They act as emulsifiers, helping to mix ingredients such as oil and water that would not otherwise blend well. Triglycerides are formed by combining glycerol with three molecules of fatty acid. Basically, If only one long-chained carboxylic acid is bonded, it is called a monoglyceride. If only two are bonded, it is called a diglyceride. Only with three is it called a triglyceride. Diglyceride Triglyceride

10. Structure: Proteins Proteins are made of Amino Acids, which are composed of carbon, nitrogen, oxygen, hydrogen and sometimes sulfur. Protein synthesis: Amino acids attach to each other by condensation to form covalent peptide bonds.Two amino acids condense to form a dipeptide, 3 form a tripeptideand many joined together form a polypeptide. Formation of a dipeptide: If more than 100 amino acids attach together it is considered a protein.

11. Structure: Proteins (cont.) Primary structures in protein: Secondary structures in protein: Primary is the term used to describe the order of the amino acids joined together to make the protein. If the “R” groups in the Amino Acid structure is replaced you would have the primary structure of a particular protein. Within the long protein chains there are regions in which the chains are organised into regular structures known as alpha-helices (alpha-helixes) and beta-pleated sheets. These are the secondary structures in proteins. These secondary structures are held together by hydrogen bonds. General 2-amino acid: B pleated sheet: Alpha Helix: In an alpha-helix, the protein chain is coiled like a loosely-coiled spring. In a beta-pleated sheet, the chains are folded so that they lie alongside each other. Primary structure:

12. Structure: Proteins (cont.) Tertiary structures in protein: Quaternary structures in protein: The tertiary structure of a protein is a description of the way the whole chain (including the secondary structures) folds itself into its final 3-dimensional shape. A protein has quaternary structure if it is formed of 2 or more subunits (polypeptides).  They are held together by various forces including hydrophobic interactions, H-bonds and ionic bonds. Tertiary structure: Quaternary structure: The model shows the alpha-helices in the secondary structure as coils of "ribbon". The beta-pleated sheets are shown as flat bits of ribbon ending in an arrow head. The bits of the protein chain which are just random coils and loops are shown as bits of "string".

13. Nutrition Expedition Presentation by: Sharina Wilson This concludes my presentation on Macromolecules!