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MARK BARTLETT, PHD. Vice President, Global Research and Development Pharmanex. DIE YOUNG. ..as late in life as possible. Our product development efforts and investment enable us to CONTINUALLY REFRESH the vibrancy of the business opportunity through PRODUCT INNOVATION.

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Mark bartlett phd
MARK BARTLETT, PHD

Vice President,

Global Research and Development

Pharmanex


DIE YOUNG

..as late in life as possible


Our product development efforts and investment enable us to CONTINUALLY REFRESH the vibrancy of the business opportunity through PRODUCT INNOVATION


Our anti-aging product strategyis to leverage LEADING EDGE SCIENCE to further understand the aging process.

  • Science in product development

    • Discovery process

    • Development process

  • Scientific assets

    • Multiple unique tools to discover and develop anti-aging products with meaningful benefits


AGELOC GENE TECHNOLOGY

GENE EXPRESSION IN YOUNG TISSUE

GENE EXPRESSION IN OLD TISSUE

OLD GENE EXPRESSIONAFTER AGELOC

Gene Expression Scale

Low

Expression

High

Expression

FIGURE DESCRIPTION: This heatmap illustrates gene expression of three groups from a pre-clinical test with one of the ageLOC Vitality ingredients: young (column 1), old (column 2), and old with ageLOC science (column 3). Each row represents one of 52 genes comprising the mitochondrial Youth Gene Cluster (mtYGC). Columns 1 and 2 show that each of the 52 genes became more or less active during the aging process. In column 3, the YGC activity pattern of the old with ageLOC science group has been reset to a gene expression pattern similar to the young group in column 1.1

1Transcriptional Biomarkers of Mitochondrial Aging and Modulation by CordycepsSinensis Cs-4. Gordon Research Conference, Biology of Aging, Determinants of Health-Span: From Cells to Humans, August 22-27, 2010. Les Diablerets Conference Center, Les Diablerets, Switzerland.


6S Quality Process

Selection; Sourcing; Standardization;

Safety; Structure; Substantiation


Anti aging product development process
ANTI-AGING PRODUCT DEVELOPMENT PROCESS

6S process

ageLOC science

TOOLKIT


R&D ENGINE - PROVO INNOVATION CENTER



New anti aging ageloc tools
NEW ANTI-AGING AGELOC TOOLS

LifeGen

  • Patented technologies to study anti-aging interventions through gene expression science

  • Acquired November 2011

NOX Technologies

  • Patented anti-aging technology

  • Incorporated in ageLOC Transformation and Galvanic Gels

  • Acquired November 2012


Healthy Aging

Nutrition Science

Antioxidant Science

GeneScience

???


Ageloc gamma weight management system
AGELOC GAMMA: WEIGHT MANAGEMENT SYSTEM

  • AN ADVANCED WEIGHT MANAGEMENT SYSTEM that incorporates gene expression science

  • ageLOC Gamma helps you look slimmer and healthier in 90 days when used in conjunction with a healthy diet and exercise

Simple Eating & Lifestyle Plan

Advanced ageLOC Products


Ageloc gamma influencing weight
AGELOC GAMMA: INFLUENCING WEIGHT

  • Key Tissues

    • There are key tissues that address critical areas of weight loss through gene expression. ageLOC Gamma will focus on these key tissues



Ageloc gamma studies
AGELOC GAMMA: STUDIES

  • LifeGen (gene expression science)

    • Gene array analysis to elucidate YGCs

  • Clinical Studies

    • Open label study (ongoing)

    • Larger trial (starting in 2013)


Gamma system
GAMMA SYSTEM

Incorporating ageLOC science and clinically demonstrated ingredients

18


Ageloc gamma represents a major innovation with gene expression science

AGELOC GAMMA REPRESENTS A MAJOR INNOVATION WITH GENE EXPRESSION SCIENCE


S3 scanner upgrade coming summer 2013
S3: SCANNER UPGRADECOMING SUMMER 2013

  • 25% smaller

  • Wireless

  • Battery operated


Future pipeline
FUTURE PIPELINE

INNOVATIVE ageLOC SKIN CARE and NUTRITION


AGELOC INNOVATION PATTERN

2010

2013

2020


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