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With Instructor: Janice R. Morabeto M.Ed. L.S.W. C.H.T. Morabeto Mind Legacy Associates Inc. Enjoy the fact that you will not have to be traveling today to get your C.E.U. hours met!

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Morabeto mind legacy associates inc

With Instructor:

Janice R. Morabeto M.Ed. L.S.W. C.H.T.

Morabeto Mind Legacy Associates Inc.


On demand training modules

Enjoy the fact that you will not have to be traveling today to get your C.E.U. hours met!

Get prepared to learn! If you normally take notes during lecture, do that as you take this On demand class. It will help you to remember what you learned better, longer and be able to apply that knowledge when you need it most!

Take advantage of downloading and printing the PowerPoint presentations before class begins.

Email me at [email protected] if you have questions regarding the content of this material, or if you are interested in future C.E.U. Opportunities.

On Demand Training Modules


Adhd a bio psycho social approach to understanding
ADHD: A bio-Psycho-Social Approach to Understanding to get your C.E.U. hours met!

The Biology Behind the Behavior


Course description

ADHD is the most common psychiatric disorder diagnosed in children in America. It remains, as well, one of the most controversial in terms of diagnosis and treatment approaches. Recently, the fields of neuroanatomy, molecular genetics and neurochemistry are beginning to shed some real light as to the complexities, and actualities of this important disorder.

Course Description


Agenda to explore the current research
Agenda: to Explore the current research children in America. It remains, as well, one of the most controversial in terms of diagnosis and treatment approaches. Recently, the fields of neuroanatomy, molecular genetics and neurochemistry are beginning to shed some real light as to the complexities, and actualities of this important disorder.


How about a little review

Take this 5 question pre-test to review and learn! children in America. It remains, as well, one of the most controversial in terms of diagnosis and treatment approaches. Recently, the fields of neuroanatomy, molecular genetics and neurochemistry are beginning to shed some real light as to the complexities, and actualities of this important disorder.

Spend only 2-3 minutes on it

Answers will be reviewed before I continue with the presentation.

How about a little review!


How can this information help you to be more effective in working with these children

Many people feel manipulated by the ADHD individual due to the inconsistencies of their behaviors.

Knowing the biology behind the behavior will help you to realize that those who suffer from ADHD have not mastered developmentally appropriate skills; ie, communication, study skills and at times are lagging in maturity

How can this information help you to be more effective in working with these children?


True false

True? False? the inconsistencies of their behaviors.


  • There are three types of ADHD. the inconsistencies of their behaviors.

  • The three subtypes of ADHD are Inattentive, Hyperactive, and Combined.

  • ADHD is a childhood disorder and evidence of it must first be seen before age 7.

    • Some of the symptoms of ADHD Hyperactive-Impulsive Type are excessive talking, difficulty in moderating impulses, and a state of general over-arousal.

    • 5. Some of the symptoms of ADHD Inattentive Type are forgetfulness, disorganization and a state of general under-arousal.


Primary symptomatology

  • Hyperactive-Impulsive Type the inconsistencies of their behaviors.

    • Hyperactivity In children

      • Inability to modulate locomotion; squirming , fidgeting, excessive climbing

    • Hyperactivity in Adults

      • Restlessness, irritability, difficulty relaxing

Primary Symptomatology


Hyperactive impulsive type cont

  • Impulsivity in children the inconsistencies of their behaviors.

    • Inability to moderate behaviors i.e. excessive talking, butting into conversations, invading others’ personal boundaries, low frustration tolerance

  • Impulsivity in Adults

    • Continue to be consistent talkers who have not learned to listen to others in a genuine way, tend to change jobs more frequently, have more divorces, traffic violations and substance abuse problems including nicotine, caffeine and overeating

Hyperactive-Impulsive Type cont.


Inattentive type

  • In children: the inconsistencies of their behaviors.

    • Difficulties in memory, listening, following directions, lack of follow through, persistence, transitioning between tasks, daydreaming.

  • In adults

    • Difficulty in memory, planning, organization, follow through in work and in family lives. Less likely to finish high school or college and tend to advance slower than their peers.

Inattentive Type


On the other hand

If they can channel their energy, enthusiasm and love of novelty, they can become very successful in the workplace.

Studies show that about 1/3 of adults with ADHD can become entrepreneurs by their 30’s.

On the other hand!


  • The human brain is the most complex structure on earth.

  • Comprised of

    • 100 billion neurons

    • Connection with cells near and far

    • Can include up to 100 trillion connections

    • 3.5 lb of gray and white matter the size of a grapefruit


  • Dynamic nature – changes constantly in response to environmental stimuli

  • Major Job – to reach and maintain Homeostasis, the regularity of the internal environment, and to integrate and modulate incoming information from our senses

  • Modulates incoming information to ascertain the bodies need for and level of response


Neuro anatomical impairments in adhd
Neuro environmental stimuli-anatomical Impairments in ADHD


Neuro anatomical impairments in adhd1

Neuro-anatomical Impairments in ADHD


Pet scan comparisons of brain waves
Pet scan comparisons of brain waves regions of the brain. Some studies suggest as much as 7-10% below the healthy control samples:


Neuro anatomical impairments in adhd2

  • Corpus Callosum regions of the brain. Some studies suggest as much as 7-10% below the healthy control samples:

  • Prefrontal Cortex

  • Basal Ganglia

  • Cerebellum

Neuro-anatomical Impairments in ADHD


Neuro anatomical impairments in adhd3

  • Locus Coeruleus regions of the brain. Some studies suggest as much as 7-10% below the healthy control samples:

  • Reticular Activating System

  • Total White Matter Volume

Neuro-anatomical Impairments in ADHD


Neuro anatomical impairments in adhd4

  • Corpus Callosum regions of the brain. Some studies suggest as much as 7-10% below the healthy control samples:

    • the large bundle of axons which connect the two cerebral hemispheres. It disseminates information from the cerebral cortex on one side of the brain to the same region on the other side.

  • Prefrontal Cortex

    • Area of the brain that is devoted to many aspects of mature adult functioning such as judgment, reasoning, planning, rational thought, organization goal setting and follow through.

Neuro-anatomical Impairments in ADHD


Neuro anatomical impairments in adhd5

  • Basal Ganglia regions of the brain. Some studies suggest as much as 7-10% below the healthy control samples:

    • group of structures which coordinate movement; located in the forebrain (telencephalon)

  • Cerebellum

    • structure located in the back of the brain involved in central regulation of movement, such as basic movement, balance, and posture; comes from the latin word meaning "little brain"; is divided into two hemispheres and has a cortex

Neuro-anatomical Impairments in ADHD


Neuro anatomical impairments in adhd6

  • Locus Coeruleus regions of the brain. Some studies suggest as much as 7-10% below the healthy control samples:

    • Noradrenergic system supplies Norepinephrine (NA) throughout the central nervous system. Involved in processing of relevant or salient information as well as highly involved in startle reactions, stress and panic.

  • Reticular Activating System

    • The RAS acts as the executive secretary conscious awareness. It is the chief gatekeeper that screens or filters the type of information that will be allowed to get through.

Neuro-anatomical Impairments in ADHD


Impairments in adhd pictorial
Impairments in ADHD: Pictorial regions of the brain. Some studies suggest as much as 7-10% below the healthy control samples:




Wellness adaptive behaviors

= Balance



  • Amino Acids neurotransmitters are

    • Glutamic acid or Glutamate Workhorses

    • GABA of the Brain

    • Aspartic acid

    • Glycine


  • Peptides neurotransmitters are

    • Vasopressin

    • Somatostatin

    • Neurotensin, etc.

    • The peptides perform specialized functions in the hypothalamus or act as co-factors elsewhere in the brain.


  • Monoamines neurotransmitters are

    • Norepinephrine,

    • Dopamine

    • Serotonin

    • Acetylcholine

      • The monoamines & acetylcholine perform specialized modulating functions and are often confined to specific structures.


  • Dopamine neurotransmitters are

    • “Gusto” Neurotransmitter

    • Implications in motivation, reward and risk taking

    • Predictive of locomotive activity


  • Norepinephrine neurotransmitters are

    • Responsible for sustained attention

    • Fight and Flight Reaction (Little Brain)

    • Prepares the body for action

    • increase the heart rate as well as blood pressure


  • Serotonin neurotransmitters are

    • Has been called the “Master neurotransmitter”

      • Has regulatory effects on other neurotrasmitters

    • Mood, appetite, concentration, memory, sexual function and arousal


Adhd brains lack neurochemical balance

  • Inattentive Type neurotransmitters are

    Norepinephrine Daydreaming

    Dopamine Memory Impairment

    Serotonin Difficulty concentrating

  • Hyperactive-Impulsive Type

    Norepinephrine Hyperactivity

    Dopamine Impulsivity

    Serontonin Restlessness

ADHD brains lack neurochemical balance


What s happening in the field of molecular genetics
What’s Happening in the Field of Molecular Genetics? neurotransmitters are

Are those people related??


Family and twin studies
Family and Twin Studies neurotransmitters are


Genetic contributions to adhd

Genetic Contributions to Adhd


Genetic contributions to adhd1

  • Dopamine D5 receptor gene (DRD5) associated with ADHD

  • Dopamine beta-hydoxylase gene (DBH)

    • Implicated in

      • Decreased concentrations of dopamine

      • Upregulated postsynaptic dopamine

        • (decreased amount available in the synapse)

      • Extracellular concentrations of dopamine

      • Brain’s inability to modulate dopamine levels to control behaviors and mental processes

Genetic Contributions to Adhd


Knock out mice

New advances in molecular genetics have enabled science to selectively “knock out” one gene in a sample of mice. By observing and contrasting generations of mice with and without a particular genetic influence behaviors can be observed, compared and contrasted.

Knock out mice


Genetic contributions to adhd2

  • Serotonin Transporter Gene (5HTTT) selectively “knock out” one gene in a sample of mice. By observing and contrasting generations of mice with and without a particular genetic influence behaviors can be observed, compared and contrasted.

  • Serotonn Receptor Gene (HTR1B)

    • Decreased concentrations of serotonin

    • Upregulated postsynaptic serotonin

      • (decreased amount available in the synapse)

    • Extracellular concentrations of serotonin

    • Brain’s inability to modulate serotonin levels to control behaviors and mental processes

Genetic Contributions to Adhd


Important note

  • The genetic contribution to ADHD has been shown to be as high as 75% in some families, but!

    • Other possible causes can be:

      • Other psychiatric disorders in parents and first degree biological relatives

      • Substance use, abuse and dependency in mother, father and alcoholism and substance related disorders in families

      • Other medical problems that could have caused damage to the brain

Important note


Whew how about a little review

Review Flash Cards under Java Games high as 75% in some families, but!

These will highlight the important aspects of the class and prepare you for the quiz.

Complete at least one more game, so that you can enjoy the review of this important information. You will also greatly increase the chances of passing the quiz the first time!

You can also review this presentation as many times as you’d like.

Whew!!! How about a little review!


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