Biomedical device laboratory
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Biomedical Device Laboratory. Dr. Duncan Maitland Associate Professor – Department of Biomedical Engineering Texas A&M University Mary Biediger John Marshall High School Northside Independent School District – San Antonio, Texas. Facts about Stroke. 750,000 cases per year

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Biomedical device laboratory

Biomedical Device Laboratory

Dr. Duncan Maitland

Associate Professor – Department of Biomedical Engineering

Texas A&M University

Mary Biediger

John Marshall High School

Northside Independent School District – San Antonio, Texas


Facts about stroke

Facts about Stroke

  • 750,000 cases per year

  • 150,000 deaths per year

    (3rd leading cause of death)

  • 30,000 hemorrhagic strokes (treatable)

  • Leading cause of disability

  • $40 billion spent on treatment and rehabilitation annually


Historical treatment since 1937

Historical Treatment (since 1937)

  • Surgical Clipping – via craniotomy

Still used

today


If it s working why change it

If it’s working, why change it?

  • Surgery on any one area may cause problems with speech, memory, muscle weakness, balance, vision, coordination, and other functions.

  • Blood clot or bleeding in the brain

  • Seizures

  • Stroke

  • Coma

  • Infection in the brain, in the wound, or in the skull

  • Brain swelling

    Source: http://health.nytimes.com/health/guides/surgery/brain-surgery/overview.html


Timelines

Timelines

  • Hospitalization – 5 to 7 days

  • Recovery time before returning to work – 6 to 12 weeks

    Source: http://www.umm.edu/news/releases/brain_aneurysm.htm


Alternative treatment since 1991

Alternative Treatment (since 1991)

Detachable coil embolization

-Can reach previously inoperable aneurysms


Risks

Risks

  • Catheter-related risks: Intra-arterial catheterization involves a risk of bleeding, infection and arterial damage.

  • Surgical risks: As with any invasive procedure, there is a slight risk of death or illness.

  • Approximately 7% of cases require additional treatment or surgery.

    Source: http://www.crrnc.com/dce.php#9


Additional complications

Additional Complications

  • Surgery time (varies with number of coils being implanted)

    • Doctors not happy

    • Patients not happy

      • Customers not happy – product less likely to sell

  • Clots forming in the blood stream

    • Problems downstream


Timelines1

Timelines

  • Hospitalization – 2 days

  • Recovery time before returning to work – about a week

    Source: http://www.umm.edu/news/releases/brain_aneurysm.htm


Cutting edge treatment

Cutting Edge Treatment

  • SMP Foam – made to fill aneurysm


Cutting edge treatment1

Cutting Edge Treatment

  • Crimped to a cylindrical shape to be fed through a micro-catheter and actuated at the site.


Why do it

Why do it?

  • Catheter and Anesthesia

  • Foam is more biocompatible

  • Healing time significantly reduced

    *This is one aspect of the work going on in the lab. It is nearly ready for animal trials, not yet used in humans.


Another treatment currently in use metal stent

Another treatment (currently in use) - Metal Stent

Reinforce the weak

artery wall

Encourage normal

blood flow

Reopen partially

blocked passages


Angioplasty vs stent

Angioplasty vs. Stent

Source: http://www.heartsite.com/html/stent.html


Stent use for aneurysm treatment

Stent use for aneurysm treatment

  • In combination with coiling

    • For “wide-neck” aneurysm.

      Source: http://www.muschealth.com/bin/h/a/stent%20bridging%20aneurysm%20neck%20to%20asisst%20coiling.jpg


In the lab

In the lab

  • SMP plastic tube


Why do this

Why do this?

  • Can you tell me


What i will do

What I will do

  • Use an MRI from a current patient


What i will do1

What I will do

  • Make a model using 3D printer


What i will do2

What I will do

  • Make a negative model


What i will do3

What I will do

  • Create a SMP plastic stent to treat the aneurysm and test it in the model.


Summary

Summary

  • Focus of the lab:

    • Design devices to treat aneurysms, fistulas, and stroke

    • Improve treatment options from what is currently used in practice

    • Use Shape Memory Polymers to create devices that will be more readily accepted by the human organism


Acknowledgements

Acknowledgements

  • TAMU E3 program

  • NSF, NPI, and TWC

  • Dr. Duncan Maitland, PhD.


Acknowledgements1

Acknowledgements

  • John Horn – Graduate student who is graciously donating his time to teaching me about the work in the lab.

  • All of the graduate students in the biomedical lab who gleefully answer my queries about their various projects.


Questions

Questions?


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