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What is protein structure?

Now that you have made a polypeptide, what type of characteristics do these chains exhibit that produce unique properties to their structure and function? Any Ideas? Structure type? Bonds?. What is protein structure?. Figure 5.18 The primary structure of a protein.

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What is protein structure?

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  1. Now that you have made a polypeptide, what type of characteristics do these chains exhibit that produce unique properties to their structure and function? Any Ideas?Structure type?Bonds?

  2. What is protein structure?

  3. Figure 5.18 The primary structure of a protein

  4. Figure 5.20 The secondary structure of a protein

  5. Figure 5.22 Examples of bonds contributing to the tertiary structure of a protein

  6. Figure 5.23 The quarternary structure of proteins

  7. Figure 5.24 Review: the four levels of protein structure

  8. Different Types of Proteins: • Fibrous – insoluble animal proteins, highly resistant to digestion • by proteolytic enzymes. • (e.g., collagen- connective tissues,30% body weight; • elastins- tendons, arteries, etc.; • keratin- hair, wool, has disulfide bridges [S-S], the more bridges the curlier the hair) • Globular – soluble in water and/or acids/bases. • (e.g., albumin- water soluble; • globulin- insoluble in water but solubility increase with NaCl, conjugate with heat • histones- water soluble, found in connection with nucleic • acids; • Conjugated – proteins combine with non-amino substances. • (e.g., nucleoproteins; glycoproteins; lipoproteins; mucoproteins; phospoproteins)

  9. Table 5.1 An Overview of Protein Functions

  10. RasMol • Rasmol is a computer modeling program. • The following exercises are designed to introduce • you to a very powerful tool scientists use to • investigate scientific questions. • The first exercise is designed to familiarize you with • the RasMolprogram. • The second exercise is designed to demonstrate • how a scientist can use this type of a program • to visualize how a particular mutation could alter • the function of a protein.

  11. RASMOL You will perform these exercises during this class period should time allow. You may download these exercises from the website at www.biology.uky.edu/bio150labs . This Rasmol exercise is your first assignment which is due at the beginning of your next class along with the flow sheet for Module 2.

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