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Kidney biopsies at Southampton General Hospital, UK

Kidney biopsies at Southampton General Hospital, UK. Dr Pankaj Deshpande. SGH. Kidney biopsies between Jan 2001 to Oct 2003 24 children identified 17 boys, 7 girls Age range: 2 years to 16 years. Exclusion criteria. Children with nephrotic syndrome who had haematuria

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Kidney biopsies at Southampton General Hospital, UK

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  1. Kidney biopsies at Southampton General Hospital, UK Dr Pankaj Deshpande

  2. SGH • Kidney biopsies between Jan 2001 to Oct 2003 • 24 children identified • 17 boys, 7 girls • Age range: 2 years to 16 years

  3. Exclusion criteria • Children with nephrotic syndrome who had haematuria • Children with HSP who had a kidney biopsy for persistent proteinuria

  4. Demographics

  5. Features • 6 children with associated proteinuria (2 nephrotic range) • 2 children with renal dysfunction(1 male, 1 female) • 2 children with familial haematuria • Except for haematuria, no complications of the biopsy

  6. Haematuria

  7. Results • 6 children with proteinuria (5 boys, 1 girl) MCGN, 3 Alport’s and 2 IgA • 3 children with familial haematuria 2 normal, 1 Alport’s • 2 children with renal dysfunction PSAGN

  8. Literature • Birmingham Childrens’ Hospital • Renal biopsies in 322 children • 1975-1996 • Continuous microscopic / recurrent macroscopic haematuria for > 6 months

  9. Results • IgA 78 children (24%) (61/17::M:F) • Alport 86 children (27%) (50/36) • Thin basement membrane 50 (15%) (18/32) • Hilar vasculopathy 28 (9%) (23/5) • Miscellaneous 32 (10%) (14/18) • Normal 48 (15%) (32/16)

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