1 / 124

Literature Supporting The Use Of Dietary Nucleotides

?Dietary nucleotides have been shown to have important effects on several components of the immune system: they may enhance intestinal absorption of iron; they affect lipoprotein and long-chain polyunsaturated fatty acid metabolism; they may alter intestinal flora; and they have been demonstrated to

duff
Download Presentation

Literature Supporting The Use Of Dietary Nucleotides

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

    1. Literature Supporting The Use Of Dietary Nucleotides Dr. Garry Gordon MD, DO, MD(H)

    2. Dietary nucleotides have been shown to have important effects on several components of the immune system: they may enhance intestinal absorption of iron; they affect lipoprotein and long-chain polyunsaturated fatty acid metabolism; they may alter intestinal flora; and they have been demonstrated to have trophic effects on the intestinal mucosa and liver in several experimental situations. Clinical studies have shown nucleotide supplementation of infant formula reduces the incidence of diarrheal episodes Cosgrove M. Nucleotides. Nutrition 1998;14:74851. DIETARY NUCLEOTIDES

    3. RNA CONTAINING FOODS CURRENTLY ON THE MARKET IMPACT (novartis/sandoz) Primary indications: Trauma Major Surgery Infections of pneumonia Cancer Ventilator dependent Burn Injury

    4. There have been numerous studies of the clinical, immunological, nutritional and biochemical effects of IMPACT. benefits were clinically confirmed by a significant reduction in infection rates and a reduction in wound healing complications, while average length of admission fell (Senkal et al. 1997) Clinically, this group had a significantly shorter length of hospital stay, a lower sepsis score and a trend to decreased infection. (Braga et al. 1996) Complication rates and length of hospital stay were reduced (Daly et al. 1995) RNA CONTAINING FOODS CURRENTLY ON THE MARKET

    5. SMA Baby Food contains added nucleotides which have been shown to be involved in the development of an infants immune system and may also reduce the incidence of diarrhoeal disease in babies. Advanced Formula ENFAMIL (Mead Johnson) Nucleotide levels in ENFAMIL are patterned after the actual average free nucleotide levels found in breast milk. RNA CONTAINING FOODS CURRENTLY ON THE MARKET

    6. Breast milk has been reported to contain 1-12 mg/dL of DNA and 10-60 mg/dL of RNA. Sanguansermsri J, 1974 Am. J. Clin. Nutr. 2: 859

More Related