Viruses. Human Immunodeficiency Virus. http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter24/animation__hiv_replication.html. Human immunodeficiency virus ( hiv ). HIV = (virus)/AIDS = (Disease) Kills/damages immune system
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Human Immunodeficiency Virus
HIV: Retrovirus with ssRNA, RT (from viral RNA to DNA), and envelope with gp120 spikes.
Gp120 attach to CD4on Helper T cells, M, dendritic cells.
Function of RT?
Provirus latent or directs active viron synthesis
HIV evades IS via latency, vacuoles, antigenic change
Diagnoses of HIV Infection, by Age
In 2010, the estimated number of diagnoses of HIV infection in the 46 states with confidential name-based HIV infection reporting, by age at diagnosis, was as follows: