1 / 7

2. Synthetic Utilization of pentafulvenes

2. Synthetic Utilization of pentafulvenes. NIIST. 2. Development of Synthetic Methodologies towards Fused Cyclooctanoids. Some of the Biologically active cyclooctanoids. Developed a Novel Methodology for the synthesis of 5-8 fused Cyclooctanoids. Tet. Lett . 2005, 46, 4785-4788. NIIST.

devi
Download Presentation

2. Synthetic Utilization of pentafulvenes

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. 2. Synthetic Utilization of pentafulvenes

  2. NIIST 2. Development of Synthetic Methodologies towards Fused Cyclooctanoids Some of the Biologically active cyclooctanoids • Developed a Novel Methodology for the synthesis of 5-8 fused Cyclooctanoids Tet. Lett. 2005, 46, 4785-4788

  3. NIIST Utilization of the Developed Synthetic Methodology Tet. Lett. 2005, 46, 4785-4788 Tetrahedron, 2006, 5952-5961 Tetrahedron, 2006, 62, 12345; Synthesis, 2006,11, 1811-1818 Eur. J. Org. Chem. 2007, 5847

  4. NIIST • Novel route to eleven membered rings and spirocyclic cyclooctanoids Synthesis, 2008, 13, 2134 Eur. J. Org. Chem. 2007, 5847 “Heterocycles via Pyrylium and Pyridinium Betaines”, K. V. Radhakrishnan, Topics in Heterocyclic Chemistry,Vol. Synthesis of Heterocycles via Cycloadditions, 13, 2008, pages-71-98.,Springer.

  5. NIIST 3. Synthetic Carbohydrate Chemistry • Design, Synthesis and Host-Guest Evaluation of Neoglycoconjugates Ionic liquid [bmim]PF6 Mediated Synthesis of 1,2-Orthoesters of Carbohydrates • 1,2-Orthoesters- Important Intermediates in Synthetic Carbohydrate Chemistry For eg: n-Pentenyl Orthoesters as Glycoside Donors • We have developed a facile and environmentally benign method for the • synthesis of 1,2- orthoesters of carbohydrates and Glycosidation reactions of • NPOE in ionic liquid [bmim]PF6. • The method is much simpler and the solvent can be reused several times Synlett, 2005, 6, 997 Bull. Chem. Soc. Jpn. 2007, 553.

  6. Synthesis and Study of Carbohydrate Appended Mutivalent ligands • Synthesis of higher order glycoconjugates as probes to define the molecular nature of carbohydrate-receptor interactions • Interaction of metal ions with carbohydrates is an important element for • biochemical processes • Metal complexes involving carbohydrates clarify many functions of carbohydrates in natural systems Carbohydrates as Scaffolds by attaching a chelating ligand for cation and anion binding

  7. NIIST Synthesis and study of Carbohydrate-coated Nanocapsules • Photochromic nanocapsules • Multivalent nanoscaffolds for selective interactions Able to encapsulate guest molecules Target selective nanocarriers Vesicles Labelling specific protein Sensing of a range of pathogens. Nanorods

More Related