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Pine Manor College
March 5, 2008
Which of these people has heart disease???
Cite prevalence and incidence data of heart disease
Identify major ethnic and gender differences in heart disease prevalence and incidence
Identify the major structures of the heart, including atria, ventricles and valves
Understand the basis of the cardiac action potentialObjectives
How many people die of heart disease in the United States each year?
What is the projected cost of heart disease for 2006, including health care services, medications, and lost productivity?
a. 100 million
b. 750 million
c. 100 billion
d. 250 billion
In 2003, what percentage of adults reported having two or more of six risk factors for heart disease and stroke?
a. 0 – 24 %
b. 25 – 49 %
c. 50 – 74%
d. 75 – 100%
What about Ethnicity? (CVD)
The Heart: Anatomy (CVD)
a. 100 gallons
b. 1000 gallons
c. 2000 gallons
d. 5000 gallons
Cardiac Muscle - striated due to arrangement of myosin and actin - adjacent cells are joined end to end by intercalated disks - adjacent cells are electrically linked by gap junctions
Conducting system of the heart
How many times does the human heart “beat” (expand and contract) in a day?
Ion channel permeability during Action Potential
A. Clinical – EKG
B. Cellular - Action Potential
C. Molecular – Electrophysiology recordings