DNA R eplication -III. Initiation of Replication. The origin of replication in E. coli is termed oriC ori gin of C hromosomal replication Important DNA sequences in oriC AT-rich region DnaA boxes. DNA Polymerase III Is the Replicative Polymerase in E. coli.
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The problem is solved by telomerase occurs in steps, starting with the binding of DnaA initiator protein, which melts an A═T-rich region.