Protein

1. Protein Junho Sung 9L Feb. 07, 2014

2. Protein: Large biological molecules ---- amino acid residues History Dutch chemist: Gerardus Johannes Mulder described first Named by: Swedish chemist Jons Jacob Berzelius in 1838 In 1958: Max Perutz and Sir John Cowdery Kendrew first protein structures to be solved  Hemoglobin and Myoglobin In 2013:the Protein Data Bank has more than 90,000 atomic-resolution structures of proteins

3. Protein - Most important substances 16 percent of total body weight. connective tissues, skin, hair and muscle What does protein do for the body? • Build Muscles, Bones and Other Body Parts • Increase Immunity • Balance pH Value • Transport Nutrient • Lose Weight

4. Lack of protein • Weak and sore muscles • Increased water retention • Flakiness, dry skin and rashes • Lethargy • Weight loss • Anxiety • Nausea • Skin ulcers • Bed sores • Deep line formations around the toes and nails • Stubborn wounds that do not heal • Constant headaches • Insomnia • Moody feelings • Blackouts • Depression • Skin color changes

5. How is a person diagnosed with the condition? • I don’t eat oily food------but I’ve got fatty liver • I wash and care my hair everyday---but my hair isdry and no shine. • My skin has deep wrinkles and no elasticity. • I do not eat much, but I cannot digest well. • I’ve got a bad temper and easy to be annoyed. What is the type of test done? • Simple blood test • A blood test can be done to see how much of this protein you have in your blood.

6. Protein Deficiency Disorder Marasmus Young children and infants severe lack of important nutrients causes weight loss, and dehydration Kwashiorkor severe malnutrition disease common in older children swollen stomach due to fluid retention irritability, diarrhea, fatigue, limited growth cognitive development as well as mental health. Cachexia causes the weakening of the skeletal muscles associated with chronic diseases like AIDS, cancer, chronic kidney failure chronic obstructive pulmonary disease and rheumatoid arthritis

7. Protein C and Protein S Deficiency 1 in every 300 people suffers from the lack of Protein CProtein S deficiency affects 1 in 20,000 people hereditary disease leading to blood clotting Anyone affected by Protein diseases- avoid activities that tend to clot the blood. Ex: bed rest, sitting for a long time in cars, airplanes and transport systems • Protein deficiency: • people who live in impoverished communities • the elderly: lack access to nutritious food • affects people:geneticdisorder to produce certain proteins

8. Protein Deficiency Treatments • Protein Supplements efficient protein supply to the body should be in just the right amount Finding the right balance of protein is challenging • Protein Rich Foods Consumption of foods enriched with proteins is essential Daily protein intake depends on the body’s needs, and it varies from adults, children, and sick people effective way to rebuild muscles effective solution for weight loss programs

10. 5 interesting facts about protein • The protein: 10~35% of person’s daily caloric intake. • Human body has 100,00 different types of protein • If people overdose the protein, it can be dangerous to our body • People are using animal protein more than plant protein. • Protein does many job in our body. For example, protein called rhodopsin helps to see light.

11. Organization and web link • http://lectures.molgen.mpg.de/ProteinStructure/Levels/ • http://www.tusculum.edu/faculty/home/ivanlare/html/genetics/protein-master.html • http://www.biologyreference.com/Po-Re/Protein-Structure.html#b

12. Bibliography • http://facts.randomhistory.com/protein-facts.html • http://learn.genetics.utah.edu/content/molecules/prions/ • http://www.med-health.net/protein-deficiency-diseases.html • http://www.meddean.luc.edu/newswire/news/modified-protein-could-become-first-effective-treatment-vitiligo-skin-disorder-loyola • http://ajcn.nutrition.org/content/74/1/6.long • http://facts.randomhistory.com/protein-facts.html