Power of Endorphin by Placebo effect. Group 3. HOPE vs. EPOH group. HOPE group: 74% of patients responded to the drugs. EPOH group: only 22% of patients responded to the same drugs.
Power of Endorphin by Placebo effect
HOPE group: 74% of patients responded to the drugs.
EPOH group: only 22% of patients responded to the same drugs.
ONLY difference between HOPE and EPOH group was the title of the drugs.
In the movie, with the Mesmer’s therapeutic
method, patients actually experienced easing pain
and decreasing symptoms.
HOPE vs. EPOH case
Mesmer's therapeutic method
can be almost explained by ‘placebo effect’.
Placebo means it is a substance with no specific
Placebo effect occurs when a patient's symptoms
are altered in some way by a treatment, due to
the individual psychological expectation
suggestion from an authority figure
believingthat it will work.
Placebo means ‘I will please him’ , which indicates
a belief that the effect was due to a subconscious
desire of the patient to please the doctor.
Physiological aspect (PAG)
Injection of placebo
Secretion of endogenous opioid
Activation of opiate receptors
Reduction of pain
Morphine injected : 70%
Placebo injected : 35%
Injection of Naloxone
provided the first direct evidence that the brain’s
own pain-relieving chemicals,
endorphins play a role in the placebo effect.
Expectation and belief by patient him/herself
(HOPE group, Mesmer’s method, Placebo effect)
Raising biological process
(Secretion of Endorphin, etc)
Symptom, pain are eased