1 / 2

btk antibody

Anti-BTK polyclonal antibody can be provided from Creative Diagnostics.<br>https://www.creative-diagnostics.com/Anti-BTK-PAb-222926-147.htm<br>

creatived11
Download Presentation

btk antibody

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Anti-BTK (N-terminal) polyclonal antibody (DPAB- Anti-BTK (N-terminal) polyclonal antibody (DPAB- L20215) L20215) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION PRODUCT INFORMATION Antigen Description Antigen Description The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013] Immunogen Immunogen BTK antibody was raised against a synthetic peptide corresponding to 16 amino acids near the amino-terminus of human BTK. Source/Host Source/Host Rabbit Species Reactivity Species Reactivity Human Conjugate Conjugate Unconjugated Applications Applications immunocytochemistry: suitable Format Format Buffered aqueous solution Size Size 100μg Buffer Buffer Supplied in PBS with 0.02% sodium azide. Storage Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C GENE INFORMATION GENE INFORMATION Gene Name Gene Name BTK Bruton agammaglobulinemia tyrosine kinase [ Homo sapiens (human) ] Official Symbol Official Symbol BTK Synonyms Synonyms BTK; Bruton agammaglobulinemia tyrosine kinase; AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1; tyrosine-protein kinase BTK; B-cell progenitor kinase; agammaglobulinaemia tyrosine kinase; truncated Bruton agammaglobulinemia tyrosine kinase; tyrosine-protein kinase BTK isoform (lacking exon 14); dominant-negative kinase-deficient Brutons tyrosine kinase 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved

  2. Entrez Gene ID Entrez Gene ID 695 mRNA Refseq mRNA Refseq NM_000061 Protein Refseq Protein Refseq NP_000052 MIM MIM 300300 UniProt ID UniProt ID Q06187 Pathway Pathway Activated TLR4 signalling; Adaptive Immune System; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; B Cell Receptor Signaling Pathway; B cell receptor signaling pathway; BCR signaling pathway; Class I PI3K signaling events; DAP12 interactions Function Function ATP binding; identical protein binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; phosphatidylinositol-3,4,5-trisphosphate binding; protein binding; protein tyrosine kinase activity; protein tyrosine kinase activity 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved

More Related