Overview of catabolic pathways. Catabolism of glucose via glycolysis and the citric acid cycle . NADH. NADH, FADH 2. Converts: 1 glucose 2 pyruvate. Net reaction of glycolysis. +. Two molecules of ATP are produced Two molecules of NAD + are reduced to NADH.
Transfer of a phosphorylgroup from ATP to glucose
Isomerization of glucose 6-phosphateto fructose 6-phosphate
enzyme: glucose 6-phosphate isomerase
Carbon 3 – Carbon 4bond cleavage, yielding twotriose phosphates
1. Aerobicconditions: pyruvate is oxidized to acetyl CoA, which enters the citric acid cycle for further oxidation
2. Anaerobicconditions (microorganisms): pyruvate is converted to ethanol
3. Anaerobicconditions (muscles, redbloodcells): pyruvate is converted to lactate