Overview of catabolic pathways. Catabolism of glucose via glycolysis and the citric acid cycle . NADH. NADH, FADH 2. Converts: 1 glucose 2 pyruvate. Net reaction of glycolysis. +. Two molecules of ATP are produced Two molecules of NAD + are reduced to NADH.
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
Converts: cycle 1 glucose2 pyruvateNet reaction of glycolysis
Glucose + 2 ADP + 2 NAD+ + 2 Pi
2 Pyruvate + 2 ATP + 2 NADH + 2 H+ + 2 H2O
Transfer of a phosphorylgroup from ATP to glucose
Isomerization of glucose 6-phosphateto fructose 6-phosphate
enzyme: glucose 6-phosphate isomerase
Transfer of a second cycle phosphoryl group from ATP to fructose 6-phosphate
Carbon 3 – Carbon 4bond cleavage, yielding twotriose phosphates
1. Aerobicconditions: pyruvate is oxidized to acetyl CoA, which enters the citric acid cycle for further oxidation
2. Anaerobicconditions (microorganisms): pyruvate is converted to ethanol
3. Anaerobicconditions (muscles, redbloodcells): pyruvate is converted to lactate
Glucose + 2 P (PEP)i2- + 2 ADP3-
2 Lactate- + 2 ATP4- + 2 H2OReduction of pyruvate to lactate
Glucose transport (PEP)into the cellFig 11.13