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Cerebral Spinal Fluid & The Meninges

Cerebral Spinal Fluid & The Meninges. Protection of the Brain. The Skull. Cranial Meninges. Cerebrospinal Fluid. Blood-Brain Barrier. Cranial Meninges - 3 layer protective membrane. 1. Dura Mater - Composed of two layers: a) Periosteal – outer layer, attaches to bone.

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Cerebral Spinal Fluid & The Meninges

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  1. Cerebral Spinal Fluid&The Meninges

  2. Protection of the Brain The Skull Cranial Meninges Cerebrospinal Fluid Blood-Brain Barrier

  3. Cranial Meninges - 3 layer protective membrane 1.Dura Mater - Composed of two layers: a) Periosteal – outer layer, attaches to bone. b) Meningeal – inner layer, closer to brain. Two layers fused, except to enclose the dural sinuses 2.Arachnoid Layer - ‘spider’ web like. 3. Pia Mater - delicate, follows convolutions.

  4. Cranial Meningeal Spaces Epidural space Potential space superior to dura. Subdural space Potential space between dura and arachnoid mater. Subarachnoid space Filled with CSF Contains the blood vessels supplying brain.

  5. The Sinuses

  6. Cerebrospinal Fluid (CSF) Roles of CSF: 1. Cushions and insulates delicate nervous tissue. 2. Gives Buoyancy to the brain (“floats” in CSF). 3. Exchange of gases (O2 and CO2), nutrients and wastes. * CSF formed in the choroid plexuses in ventricles of brain

  7. Blood Brain Barrier (BBB) A restrictive barrier around blood vessels in the brain (created by astrocytes). Prevents most blood-borne toxins from entering the brain but not an absolute barrier. Nutrients such as O2, and glucose can pass. Plus CO2, alcohol, nicotine, and anesthetics. Dopamine? L-Dopa?

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