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Vitamin B1 in Camels

Vitamin B1 in Camels. Vitamin B1 (thiamine)( Aneurin ). Chemical properties. Where can we found it? Vitamin B1 & chemical interaction. Thiamine pathway inside the camel. Thiamine derivatives (TMP)(TDP)(ATDP)(TTP)(ATTP)(free Thiamine). Methods of thiamine analysis. Importance of thiamine.

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Vitamin B1 in Camels

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  1. Vitamin B1 in Camels

  2. Vitamin B1 (thiamine)(Aneurin) • Chemical properties. • Where can we found it? • Vitamin B1 & chemical interaction. • Thiamine pathway inside the camel. • Thiamine derivatives (TMP)(TDP)(ATDP)(TTP)(ATTP)(free Thiamine). • Methods of thiamine analysis.

  3. Importance of thiamine • Metabolism of carbohydrates & proteins and fats. • ATP production. • Myelin sheath production. • Anti-stress. • Electrolyte balance. • Life spam of RBCs. • Pregnant camel.

  4. Vitamin B1 deficiency in camelPolioEnchephaloMalacia (PEM) • Origin of the name • Deficiency depend on (purpose of breading & age & sex & type of production).

  5. Average thiamine in camel blood

  6. Average thiamine in blood of camel (39 ± 11.5 µg/L). Minimum average of thiamine in blood of camel that clinical signs of PEM appear below it (20 ± 10.4 µg/L).

  7. Polioencephalomalacia • Definition. • Predisposing causes. Impaction Toxic plants Sulphur NSAIDs Lead toxicity thapendazole Antibiotic milk Amprolium stress Purgatives magnesium Selenium toxicity B.cereus

  8. Geographical distributions. • Susceptible camels. • Morbidity and mortality percent. • Pathogeneses.

  9. Wry neck disease

  10. Polioencephalomalacia in young camel

  11. PM signs. • Diagnosis: 1- case history. 2- clinical signs. 3- differential diagnosis. 4- laboratory diagnosis.

  12. Laboratory diagnosis • Hematology (WBCs & Neutrophile). • Biochemistry(Liver enzymes & Mg). • Water and food analysis (Sulphur). • B1 analysis: 1- Erythrocyte Transketolase Activation Assay (ETAA). 2- High Performance Liquid Chromatography (HPLC).

  13. Treatment • Primary: 1- vitamin B1 injection. 2- corticosteroid injection. 3- B complex injection. 4- maintenance by vitamin B1 powder with magnesium. • Secondary: 1- antacid. 2- fluid thereby. 3- antibiotic. 4- purgatives. 5- stop using water containing high sulphur. 6- stop using medicines causing B1 deficiency.

  14. Prevention • Nutrition correction. • Not using antibiotic that kill the rumen flora. • Not using NSAIDs for long time. • Amprolium, thiapendazole, sulphur, lead,selenium. • Water sources. • Poisonous plants. • Bacillus vaccination (R/Neobacter). • Periodical laboratory tests.

  15. Racing camel • Importance of vitamin B1 for racing camel. • Uses. • Research for B1 analysis in racing camel in Dubai.

  16. Racing camel recommendations • Perminant source of oral B1 (R/Karma – R/ Ultra B1). • Periodical B1 injection. • Periodical B1 laboratory test. • Using by low concentration before racing. • Using of bicarbonate salts. • Average B1 in blood by (HPLC) = (56 ± 12 µg/L) • Average border line for B1 deficiency by (HPLC) = (21 ± 10.4 µg/L).

  17. Thank you Dr.MedhatElshemy

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