Genetic Variation in Individuals and Populations: Mutation and Polymorphism . Lecture 8. FACTORS THAT DISTURB HARDY-WEINBERG EQUILIBRIUM. A number of assumptions underlie the Hardy-Weinberg law: Population is large and mating is random .
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3. Selection for or against particular alleles and new mutations adding alleles are not significant
Genetic Drift in Small Populations
μ = sq
μ = sq / 3
Drift Versus Heterozygote Advantage hemoglobin C, the thalassemias, and glucose-6-phosphate dehydrogenase deficiency, as well as the benign