Hormonal control of male reproductive functions
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Hormonal Control of Male Reproductive Functions. Hormones are secreted by: Hypothalamus Anterior pituitary gland Testes Functions: Development of sperm cells Development of secondary sex characteristics. Hypothalamic and Pituitary Hormones.

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Hormonal Control of Male Reproductive Functions

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Hormonal control of male reproductive functions

Hormonal Control of Male Reproductive Functions

  • Hormones are secreted by:

    • Hypothalamus

    • Anterior pituitary gland

    • Testes

  • Functions:

    • Development of sperm cells

    • Development of secondary sex characteristics


Hypothalamic and pituitary hormones

Hypothalamic and Pituitary Hormones

  • Hypothalamus secretes gonadotropin-releasing hormone (GnRH) to anterior pituitary gland

  • In response, anterior pituitary gland secretes gonadotropins:

    • Luteinizing hormone (LH)

    • Follicle-stimulating hormone (FSH), aka interstitial cell-stimulating hormone (ICSH)


Hypothalamic and pituitary hormones continued

Hypothalamic and Pituitary Hormones, continued…..

  • FSH (ICSH) promotes development of ___________.

  • Testicular interstitial cells secrete male sex hormones.

  • LH stimulates supporting cells of seminiferous tubules to respond to testosterone.


Hypothalamic and pituitary hormones continued1

Hypothalamic and Pituitary Hormones, continued…..

  • FSH + testosterone + supporting cells stimulate spermatogenic cells to give rise to ______________.

  • Supporting cells secrete inhibin, a hormone which inhibits the anterior pituitary gland, preventing secretion of FSH.


Male sex hormones

Male Sex Hormones

  • Called “Androgens” (???)

  • Where are they produced?

  • Most in testicular interstitial cells, but small amounts in adrenal cortex

  • What is the main male sex hormone?

  • Testosterone production begins before birth, continues a few weeks after, and then ceases until puberty.


Actions of testosterone

Actions of Testosterone

  • Stimulates enlargement of testes and male accessory organs

  • Stimulates development of male secondary sex characteristics:

    • Increased growth of body hair

    • Enlargement of the larynx and thickening of the vocal cords

    • Thickening of the skin

    • Muscle growth, widening of shoulders, narrowing of waist

    • Thickening and strengthening of bones


Actions of testosterone continued

Actions of Testosterone, continued…..

  • Increases rate of cellular metabolism

  • Increases rate of RBC production


Regulation of male sex hormones

Regulation of Male Sex Hormones

  • More testosterone = more developed secondary sex characteristics

  • Increased levels of testosterone inhibit the hypothalamus.

  • What effects would inhibition of the hypothalamus have?


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