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A. Bcl-xL -/-. Bcl-xL +/+. B. Mcl-1 -/-. Mcl-1 +/+. Supplementary Fig. 1. A. Bcl-xL -/- No.1 T1. Bcl-xL -/- No.3 T1. Bcl-xL +/+. Bcl-xL -/- No.1NT. Bcl-xL -/- No.1 T2. Bcl-xL -/- No.2 NT. Bcl-xL -/- No.2 T1. Bcl-xL -/- No.2 T2. Bcl-xL -/- No.2 T3. Bcl-xL -/- No.3 NT.

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Supplementary Fig. 1

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Supplementary fig 1

A

Bcl-xL-/-

Bcl-xL+/+

B

Mcl-1-/-

Mcl-1+/+

Supplementary Fig. 1


Supplementary fig 1

A

Bcl-xL-/-No.1 T1

Bcl-xL-/-No.3 T1

Bcl-xL+/+

Bcl-xL-/-No.1NT

Bcl-xL-/-No.1 T2

Bcl-xL-/-No.2 NT

Bcl-xL-/-No.2 T1

Bcl-xL-/-No.2 T2

Bcl-xL-/-No.2 T3

Bcl-xL-/-No.3NT

Bcl-xL-/-No.4 NT

Bcl-xL-/-No.4 T1

Bcl-xL-/-No.4 T2

Bcl-xL-/-No.4 T3

Bcl-xL-/-No.5 NT

Bcl-xL-/-No.5 T1

Bcl-xL+/+

Bcl-xL+/+

Bcl-xL+/+

Beta actin

Mcl-1

B

Mcl-1-/-No 1 T1

Mcl-1-/-No 4 T1

Mcl-1-/-No 6 T1

Mcl-1+/+

Mcl-1-/-No.1 NT

Mcl-1-/-No 2 NT

Mcl-1-/-No 2 T1

Mcl-1-/-No 3 NT

Mcl-1-/-No 3 T1

Mcl-1-/-No 3 T2

Mcl-1-/-No 3 T3

Mcl-1-/-No 3 T4

Mcl-1-/-No 4 NT

Mcl-1-/-No 4 T2

Mcl-1-/-No 5 NT

Mcl-1-/-No 5 T1

Mcl-1-/-No 5 T2

Mcl-1-/-No 5 T3

Mcl-1-/-No 6 NT

Mcl-1-/-No 6 T2

Mcl-1+/+

Mcl-1+/+

Beta actin

Bcl-xL

Supplementary Fig.2


Supplementary fig 1

Bcl-xL-/-Tumor

Mcl-1-/-Tumor

Supplementary Fig.3


Supplementary fig 1

A

Mcl-1-/-

Mcl-1+/+

Bak+/+

Bak-/-

Bak+/+

Bak-/-

Ki67

B

*

*

*

Ki-67 positvenucli

(-/-)

(-/-)

Bak

(+/+)

(+/+)

Mcl-1+/+

Mcl-1-/-

SupplementaryFig. 4


Supplementary fig 1

*

Sirius red stained area (%)

(-/-)

Bak

(+/+)

Mcl-1-/-

Bak+/+Mcl-1-/-

Bak-/-Mcl-1-/-

SupplementaryFig. 5


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