Rapidly Growing Biomaterials Market is Driven by Several Potential Applications

1. Biomaterials Market- A Global and Regional Analysis Table of Content Focus on Applications, Product Types, and Countries Analysis and Forecast: 2021-2031 Global Biomaterials Market September 2021 All rights reserved at BIS Research Inc. 1

2. BIS Research is a leading market intelligence and technology research company. BIS Research publishes in- depth market intelligence reports focusing on the market estimations, technology analysis, emerging high- growth applications, deeply segmented granular country-level market data and other important market parameters useful in the strategic decision making for senior management. BIS Research provides multi-client reports, company profiles, databases, and custom research services. Copyright © 2021 BIS Research Inc. All Rights Reserved. This document contains highly confidential information and is the sole property of BIS Research. Disclosing, copying, circulating, quoting, or otherwise reproducing any or all contents of this Global Biomaterials Market document is strictly prohibited. Access to this information is provided exclusively for the benefit of the people or organization concerned. It may not be accessed by or offered whether for sale or otherwise to any third party. All rights reserved at BIS Research Inc. 2

3. Table of Content Executive Summary ........................................................................ 26 Scope of the Study .......................................................................... 32 1 Markets .................................................................................... 35 1.1 Industry Outlook .............................................................................................. 36 1.1.1Trends: Current and Future ........................................................................ 36 1.1.2Supply Chain Network ................................................................................ 36 1.1.3Industry Attractiveness ............................................................................... 38 1.1.3.1 Threat of New Entrants (Moderate) .................................................................. 39 1.1.3.2 Bargaining Power of Buyers (Moderate) ........................................................... 40 1.1.3.3 Bargaining Power of Suppliers (Moderate) ....................................................... 40 1.1.3.4 Threat of Substitutes (Low) .............................................................................. 41 1.1.3.5 Intensity of Competitive Rivalry (High) .............................................................. 42 1.1.4Patent Analysis ............................................................................................ 42 1.1.4.1 Patent Analysis (by Status) .............................................................................. 43 1.1.4.2 Patent Analysis (by Organization) .................................................................... 44 1.2 Market Dynamics ............................................................................................. 45 1.2.1Market Driver ............................................................................................... 46 1.2.1.1 Increasing Funds/Aids by Government for Research Purposes ........................ 46 1.2.1.2 Increasing Plastic Surgery and Wound Healing Therapies ............................... 48 1.2.1.3 Increasing Aging/Geriatric Population .............................................................. 49 1.2.1.4 Rise in Prevalence of Cardiovascular Diseases ............................................... 50 1.2.1.5 Increasing Orthopedic Disorders ...................................................................... 51 1.2.1.6 Growing Demand for Implantable Devices ....................................................... 52 1.2.1.7 Increasing Awareness of Regenerative Medicine ............................................. 52 1.2.2Market Restraint .......................................................................................... 53 Global Biomaterials Market 1.2.2.1 Biocompatibility Issues and Safety and Stringent Regulations .......................... 53 1.2.2.2 Limitations of Biomaterial-Based Products ....................................................... 54 1.2.3Market Opportunity ..................................................................................... 55 1.2.3.1 Increasing Obesity ........................................................................................... 55 All rights reserved at BIS Research Inc. 3

4. 1.2.3.2 Patient Awareness and Improved Lifestyle in Emerging Economies ................. 56 1.2.3.3 Introduction of Biomaterials in Cancer Research .............................................. 56 1.2.4Business and Corporate Strategies ........................................................... 57 1.2.4.1 Key Market Development and Strategies ......................................................... 57 1.2.4.2 Product Launches and Developments .............................................................. 58 1.2.4.3 Partnerships, Collaborations, and Contracts .................................................... 60 1.2.4.4 Business Expansions ....................................................................................... 62 1.2.4.5 Mergers, Acquisitions, and Joint Ventures ........................................................ 63 1.2.4.6 Other Key Developments ................................................................................. 65 2 Application ............................................................................... 67 2.1 Global Biomaterials Market (by Application, Sub-Application and Specification) ................................................................................................... 68 2.2 Demand Analysis of Global Biomaterials Market (by Application and Sub-Application), Value and Volume Data..................................................... 68 2.2.1Cardiovascular ............................................................................................ 70 2.2.1.1 Catheters ......................................................................................................... 71 2.2.1.2 Stents ............................................................................................................... 71 2.2.1.3 Heart Valves .................................................................................................... 72 2.2.1.4 Guidewires ....................................................................................................... 72 2.2.1.5 Sensors ............................................................................................................ 72 2.2.1.6 Pacemaker ....................................................................................................... 73 2.2.1.7 Implantable Cardiac Defibrillators (ICD) ........................................................... 73 2.2.1.8 Vascular Grafts ................................................................................................ 73 2.2.2Orthopedic ................................................................................................... 74 2.2.2.1 Joint Replacement ........................................................................................... 74 2.2.2.1.1Hip Replacement...................................................................................................... 74 Global Biomaterials Market 2.2.2.1.2Knee Replacement .................................................................................................. 75 2.2.2.1.3Shoulder Replacement ............................................................................................ 75 2.2.2.1.4Other Replacement .................................................................................................. 75 2.2.2.2 Viscos Supplementation ................................................................................... 75 2.2.2.3 Bioresorbable Tissue Fixation .......................................................................... 76 All rights reserved at BIS Research Inc. 4

5. 2.2.2.3.1Suture Anchors ........................................................................................................ 76 2.2.2.3.2Interference Screws ................................................................................................. 76 2.2.2.3.3Meshes ..................................................................................................................... 76 2.2.2.4 Spine ................................................................................................................ 77 2.2.2.4.1Minimally Invasive Fusion Surgeries ....................................................................... 77 2.2.2.4.2Motion Preservation and Dynamic Stabilization ...................................................... 77 2.2.2.4.2.1Pedicle-Based-Rod Systems ............................................................................ 77 2.2.2.4.2.2Interspinous Spacers ........................................................................................ 78 2.2.2.4.2.3Disc Arthroplasty/Replacement ........................................................................ 78 2.2.2.5 Fracture Fixation .............................................................................................. 78 2.2.2.5.1Bone Plates .............................................................................................................. 78 2.2.2.5.2Screws ..................................................................................................................... 79 2.2.2.5.3Pins .......................................................................................................................... 79 2.2.2.5.4Rods ......................................................................................................................... 79 2.2.2.6 Fracture Fixation .............................................................................................. 79 2.2.2.6.1Bone Grafts .............................................................................................................. 80 2.2.3Ophthalmology ............................................................................................ 80 2.2.3.1 Contact Lenses ................................................................................................ 80 2.2.3.2 Intraocular Lenses ............................................................................................ 81 2.2.3.3 Functional Replacement of Ocular Tissues ...................................................... 81 2.2.3.4 Synthetic Corneas ............................................................................................ 82 2.2.3.5 Others .............................................................................................................. 82 2.2.4Dental ........................................................................................................... 82 2.2.4.1 Dental Bone Grafts and Substitutes ................................................................. 83 2.2.4.2 Dental Membranes ........................................................................................... 83 2.2.5Wound Healing ............................................................................................ 83 Global Biomaterials Market 2.2.5.1 Wound Closure Devices ................................................................................... 84 2.2.5.2 Sutures ............................................................................................................ 84 2.2.5.3 Staples ............................................................................................................. 84 2.2.5.4 Surgical Hemostats .......................................................................................... 85 All rights reserved at BIS Research Inc. 5

6. 2.2.5.5 Internatal Tissue Sealants ................................................................................ 85 2.2.5.6 Adhesion Barriers ............................................................................................. 85 2.2.5.7 Hernia Meshes ................................................................................................. 85 2.2.6Plastic Surgery ............................................................................................ 86 2.2.6.1 Soft Tissue Fillers ............................................................................................. 86 2.2.6.2 Craniofacial Surgery ......................................................................................... 87 2.2.7Neurological/Central Nervous System ...................................................... 87 2.2.7.1 Shunting Systems ............................................................................................ 88 2.2.7.2 Cortical Neural Prosthetics (CNP) .................................................................... 88 2.2.7.3 Hydrogel Scaffolds for CNS Report .................................................................. 88 2.2.7.4 Neural Stem Cell Encapsulation ....................................................................... 89 2.2.8Tissue Engineering ..................................................................................... 89 2.2.8.1 Scaffolds for Regenerative Medicine ................................................................ 89 2.2.8.2 Nanomaterial for Biosensing ............................................................................ 90 2.2.8.3 Tailoring of Inorganic Nanoparticles ................................................................. 91 2.2.9Others ........................................................................................................... 91 2.2.9.1 Drug Delivery Systems ..................................................................................... 91 2.2.9.2 Gastrointestinal Applications ............................................................................ 91 2.2.9.3 Bariatric Surgery .............................................................................................. 92 2.2.9.4 Urinary Applications ......................................................................................... 92 3 Products .................................................................................. 93 3.1 Global Biomaterials Market (by Product Type, Sub-Product Type and Specifications) ................................................................................................. 94 3.2 Demand Analysis of Global Biomaterials Market (by Product Type and Sub-Product Type), Value and Volume Data ................................................. 94 3.2.1Metal-Based Biomaterials ........................................................................... 96 Global Biomaterials Market 3.2.1.1 Stainless Steel ................................................................................................. 97 3.2.1.2 Titanium and Titanium alloys ............................................................................ 98 3.2.1.3 Cobalt-Chromium (Co-Cr) Alloys ...................................................................... 99 3.2.1.4 Magnesium (Mg) ............................................................................................ 100 3.2.1.5 Gold (Au) ........................................................................................................ 100 All rights reserved at BIS Research Inc. 6

7. 3.2.1.6 Silver (Ag) ...................................................................................................... 101 3.2.1.7 Nitinol ............................................................................................................. 101 3.2.1.8 Other Metal-Based Biomaterials ..................................................................... 102 3.2.2Polymer-Based Biomaterials .................................................................... 102 3.2.2.1 Polyethylene Terephthalate (PET).................................................................. 103 3.2.2.2 Polypropylene (PP) ........................................................................................ 103 3.2.2.3 Polyetheretherketone (PEEK) ........................................................................ 104 3.2.2.4 Ultra-High Molecular Weight Polyethylene (UHMWPE) .................................. 104 3.2.2.5 Polytetrafluoroethylene (PTFE) ...................................................................... 105 3.2.2.6 Polyglycolide (PGA) ....................................................................................... 105 3.2.2.7 Polyactide (PLA) ............................................................................................ 105 3.2.2.8 Polycaprolactone (PCL) ................................................................................. 106 3.2.2.9 Polyglycerol Sebacate (PGS) ......................................................................... 106 3.2.2.10 Polyvinylchloride (PVC) .................................................................................. 107 3.2.2.11 Silicone Rubber .............................................................................................. 107 3.2.2.12 Nylon .............................................................................................................. 107 3.2.2.13 Polymethyl Methacrylate (PMMA) .................................................................. 107 3.2.2.14 Other Polymer-Based Biomaterials ................................................................ 108 3.2.3Ceramic-Based Biomaterials .................................................................... 108 3.2.3.1 Alumina .......................................................................................................... 109 3.2.3.2 Calcium Phosphate ........................................................................................ 109 3.2.3.3 Zirconia .......................................................................................................... 109 3.2.3.4 Calcium Sulfate .............................................................................................. 110 3.2.3.5 Carbon ........................................................................................................... 110 3.2.3.6 Other Ceramic-Based Biomaterials ................................................................ 111 3.2.4Natural-Based Biomaterials ...................................................................... 111 Global Biomaterials Market 3.2.4.1 Collagen ......................................................................................................... 111 3.2.4.2 Fibrin .............................................................................................................. 112 3.2.4.3 Gelatin ........................................................................................................... 112 3.2.4.4 Silk ................................................................................................................. 112 All rights reserved at BIS Research Inc. 7

8. 3.2.4.5 Alginates ........................................................................................................ 113 3.2.4.6 Hyaluronic Acid .............................................................................................. 113 3.2.4.7 Chitin and Chitosan ........................................................................................ 114 3.2.4.8 Cellulose ........................................................................................................ 114 3.2.5Inorganic Glass-Based Biomaterials ....................................................... 115 3.2.5.1 Silicates.......................................................................................................... 115 3.2.5.2 Bioactive Glass .............................................................................................. 116 3.2.5.3 Phosphate ...................................................................................................... 116 3.2.6Radiopaque Biomaterials ......................................................................... 117 3.2.7Regenerative Biomaterials ....................................................................... 117 3.2.8Hybrid Biomaterial Combinations ............................................................ 118 Region ................................................................................... 119 4 4.1 North America ................................................................................................ 121 4.1.1Market ......................................................................................................... 121 4.1.1.1 Key Manufacturers and Suppliers in North America ....................................... 121 4.1.1.2 Business Drivers ............................................................................................ 121 4.1.1.3 Business Challenges ...................................................................................... 121 4.1.2Applications ............................................................................................... 122 4.1.2.1 North America Biomaterials Market (by Application and Sub-Application), Value and Volume Data ................................................................................. 122 4.1.3Product ....................................................................................................... 124 4.1.3.1 North America Biomaterials Market (by Product Type and Sub-Product Type), Value and Volume Data ...................................................................... 124 4.1.4North America (by Country) ..................................................................... 126 4.1.4.1 U.S. ................................................................................................................ 126 4.1.4.1.1Market .................................................................................................................... 126 Global Biomaterials Market 4.1.4.1.1.1Buyer Attributes .............................................................................................. 126 4.1.4.1.1.2Key Manufacturers and Suppliers in the U.S. ................................................ 127 4.1.4.1.1.3Business Challenges ...................................................................................... 127 4.1.4.1.1.4Business Drivers ............................................................................................. 127 4.1.4.1.2Application .............................................................................................................. 128 All rights reserved at BIS Research Inc. 8

9. 4.1.4.1.2.1U.S. Biomaterials Market (by Application and Sub-Application)..................... 128 4.1.4.1.3Product ................................................................................................................... 129 4.1.4.1.3.1U.S. Biomaterials Market (by Product Type and Sub-Product Type) ............. 129 4.1.4.2 Canada .......................................................................................................... 131 4.1.4.2.1Market .................................................................................................................... 131 4.1.4.2.1.1Buyer Attributes .............................................................................................. 131 4.1.4.2.1.2Key Manufacturers and Suppliers in Canada ................................................. 132 4.1.4.2.1.3Business Challenges ...................................................................................... 132 4.1.4.2.1.4Business Drivers ............................................................................................. 132 4.1.4.2.2Application .............................................................................................................. 132 4.1.4.2.2.1Canada Biomaterials Market (by Application and Sub-Application) ............... 132 4.1.4.2.3Product ................................................................................................................... 134 4.1.4.2.3.1Canada Biomaterials Market (by Product Type and Sub-Product Type) ....... 134 4.1.4.3 Mexico ........................................................................................................... 136 4.1.4.3.1.1Buyer Attributes .............................................................................................. 136 4.1.4.3.1.2Key Manufacturers and Suppliers in Mexico .................................................. 136 4.1.4.3.1.3Business Challenges ...................................................................................... 136 4.1.4.3.1.4Business Drivers ............................................................................................. 136 4.1.4.3.2Application .............................................................................................................. 137 4.1.4.3.2.1Mexico Biomaterials Market (by Application and Sub-Application) ................ 137 4.1.4.3.3Product ................................................................................................................... 138 4.1.4.3.3.1Mexico Biomaterials Market (by Product Type and Sub-Product Type) ........ 138 4.2 Europe ............................................................................................................ 142 4.2.1Market ......................................................................................................... 142 4.2.1.1 Key Manufacturers and Suppliers in Europe .................................................. 142 4.2.1.2 Business Drivers ............................................................................................ 142 Global Biomaterials Market 4.2.1.3 Business Challenges ...................................................................................... 142 4.2.2Applications ............................................................................................... 143 4.2.2.1 Europe Biomaterials Market (by Application and Sub-Application), Value and Volume Data ........................................................................................... 143 4.2.3Product ....................................................................................................... 145 All rights reserved at BIS Research Inc. 9

10. 4.2.3.1 Europe Biomaterials Market (by Product Type and Sub-Product Type), Value and Volume Data ................................................................................. 145 4.2.4Europe (by Country) .................................................................................. 147 4.2.4.1 Germany ........................................................................................................ 147 4.2.4.1.1Market .................................................................................................................... 147 4.2.4.1.1.1Buyer Attributes .............................................................................................. 147 4.2.4.1.2Key Manufacturers and Suppliers in Germany ...................................................... 147 4.2.4.1.3Business Challenges ............................................................................................. 148 4.2.4.1.4Business Drivers .................................................................................................... 148 4.2.4.1.5Application .............................................................................................................. 148 4.2.4.1.5.1Germany Biomaterials Market (by Application and Sub-Application) ............. 148 4.2.4.1.6Product ................................................................................................................... 150 4.2.4.1.6.1Germany Biomaterials Market (by Product Type and Sub-Product Type) ..... 150 4.2.4.2 France ............................................................................................................ 152 4.2.4.2.1Market .................................................................................................................... 152 4.2.4.2.1.1Buyer Attributes .............................................................................................. 152 4.2.4.2.1.2Key Manufacturers and Suppliers in France .................................................. 152 4.2.4.2.1.3Business Challenges ...................................................................................... 152 4.2.4.2.1.4Business Drivers ............................................................................................. 153 4.2.4.2.2Application .............................................................................................................. 153 4.2.4.2.2.1France Biomaterials Market (by Application and Sub-application) ................. 153 4.2.4.2.3Product ................................................................................................................... 155 4.2.4.2.3.1France Biomaterials Market (by Product Type and Sub-Product Type) ......... 155 4.2.4.3 Spain .............................................................................................................. 156 4.2.4.3.1Market .................................................................................................................... 157 4.2.4.3.1.1Buyer Attributes .............................................................................................. 157 Global Biomaterials Market 4.2.4.3.1.2Key Manufacturers and Suppliers in Spain .................................................... 157 4.2.4.3.1.3Business Challenges ...................................................................................... 157 4.2.4.3.1.4Business Drivers ............................................................................................. 157 4.2.4.3.2Application .............................................................................................................. 157 4.2.4.3.2.1Spain Biomaterials Market (by Application and Sub-Application) .................. 157 All rights reserved at BIS Research Inc. 10

11. 4.2.4.3.3Product ................................................................................................................... 159 4.2.4.3.3.1Spain Biomaterials Market (by Product Type and Sub-Product Type) ........... 159 4.2.4.4 Italy ................................................................................................................ 161 4.2.4.4.1Market .................................................................................................................... 161 4.2.4.4.1.1Buyer Attributes .............................................................................................. 161 4.2.4.4.1.2Key Manufacturers and Suppliers in Italy ....................................................... 161 4.2.4.4.1.3Business Challenges ...................................................................................... 161 4.2.4.4.1.4Business Drivers ............................................................................................. 161 4.2.4.4.2Application .............................................................................................................. 162 4.2.4.4.2.1Italy Biomaterials Market (by Application and Sub-Application) ..................... 162 4.2.4.4.3Product ................................................................................................................... 163 4.2.4.4.3.1Italy Biomaterials Market (by Product Type and Sub-Product Type) ............. 163 4.2.4.5 Russia ............................................................................................................ 165 4.2.4.5.1Market .................................................................................................................... 165 4.2.4.5.1.1Buyer Attributes .............................................................................................. 165 4.2.4.5.1.2Key Manufacturers and Suppliers in Russia................................................... 165 4.2.4.5.1.3Business Challenges ...................................................................................... 166 4.2.4.5.1.4Business Drivers ............................................................................................. 166 4.2.4.5.2Application .............................................................................................................. 166 4.2.4.5.2.1Russia Biomaterials Market (by Application and Sub-Application) ................ 166 4.2.4.5.3Product ................................................................................................................... 168 4.2.4.5.3.1Russia Biomaterials Market (by Product Type and Sub-Product Type) ......... 168 4.2.4.6 Rest-of-Europe ............................................................................................... 169 4.2.4.6.1Application .............................................................................................................. 170 4.2.4.6.1.1Rest-of-Europe Biomaterials Market (by Application and Sub- Application) ............................................................................................................ 170 Global Biomaterials Market 4.2.4.6.2Product ................................................................................................................... 171 4.2.4.6.2.1Rest-of-Europe Biomaterials Market (by Product Type and Sub-Product Type) ..................................................................................................................... 171 4.3 U.K. ................................................................................................................. 175 4.3.1Market ......................................................................................................... 175 All rights reserved at BIS Research Inc. 11

12. 4.3.1.1 Buyer Attributes .............................................................................................. 175 4.3.1.2 Key Manufacturers and Suppliers in the U.K. ................................................. 175 4.3.1.3 Business Challenges ...................................................................................... 175 4.3.1.4 Business Drivers ............................................................................................ 175 4.3.2Applications ............................................................................................... 176 4.3.2.1 U.K. Biomaterials Market (by Application and Sub-Application) ...................... 176 4.3.3Product ....................................................................................................... 178 4.3.3.1 U.K. Biomaterials Market (by Product Type and Sub-Product Type) .............. 178 4.4 China ............................................................................................................... 181 4.4.1Market ......................................................................................................... 181 4.4.1.1 Buyer Attributes .............................................................................................. 181 4.4.1.2 Key Manufacturers and Suppliers in China ..................................................... 181 4.4.1.3 Business Challenges ...................................................................................... 181 4.4.1.4 Business Drivers ............................................................................................ 182 4.4.2Applications ............................................................................................... 182 4.4.2.1 China Biomaterials Market (by Application and Sub-Application) ................... 182 4.4.3Product ....................................................................................................... 184 4.4.3.1 China Biomaterials Market (by Product Type and Sub-Product Type) ............ 184 4.5 Asia-Pacific and Japan .................................................................................. 187 4.5.1Market ......................................................................................................... 187 4.5.1.1 Key Manufacturers and Suppliers in Asia-Pacific and Japan .......................... 187 4.5.1.2 Business Drivers ............................................................................................ 187 4.5.1.3 Business Challenges ...................................................................................... 187 4.5.2Applications ............................................................................................... 188 4.5.2.1 Asia-Pacific & Japan Biomaterials Market (by Application and Sub- Application), Value and Volume Data ............................................................. 188 Global Biomaterials Market 4.5.3Product ....................................................................................................... 190 4.5.3.1 Asia-Pacific & Japan Biomaterials Market (by Product Type and Sub- Product Type), Value and Volume Data ......................................................... 190 4.5.4Asia-Pacific (by Country) .......................................................................... 192 4.5.4.1 Japan ............................................................................................................. 192 All rights reserved at BIS Research Inc. 12

13. 4.5.5Market ......................................................................................................... 192 4.5.5.1 Buyer Attributes .............................................................................................. 192 4.5.5.2 Key Manufacturers and Suppliers in Japan .................................................... 193 4.5.5.3 Business Challenges ...................................................................................... 193 4.5.5.4 Business Drivers ............................................................................................ 193 4.5.5.4.1Application .............................................................................................................. 193 4.5.5.4.1.1Japan Biomaterials Market (by Application and Sub-Application) .................. 193 4.5.5.4.2Product ................................................................................................................... 195 4.5.5.4.2.1Japan Biomaterials Market (by Product Type and Sub-Product Type) .......... 195 4.5.5.2 South Korea ................................................................................................... 197 4.5.6Market ......................................................................................................... 197 4.5.6.1 Buyer Attributes .............................................................................................. 197 4.5.6.2 Key Manufacturers and Suppliers in South Korea .......................................... 197 4.5.6.3 Business Challenges ...................................................................................... 197 4.5.6.4 Business Drivers ............................................................................................ 197 4.5.6.4.1Application .............................................................................................................. 198 4.5.6.4.1.1South Korea Biomaterials Market (by Application and Sub-Application) ....... 198 4.5.6.4.2Product ................................................................................................................... 199 4.5.6.4.2.1South Korea Biomaterials Market (by Product Type and Sub-Product Type) ..................................................................................................................... 199 4.5.6.5 India ............................................................................................................... 201 4.5.7Market ......................................................................................................... 201 4.5.7.1 Buyer Attributes .............................................................................................. 201 4.5.7.2 Key Manufacturers and Suppliers in India ...................................................... 201 4.5.7.3 Business Challenges ...................................................................................... 202 4.5.7.4 Business Drivers ............................................................................................ 202 Global Biomaterials Market 4.5.7.4.1Application .............................................................................................................. 202 4.5.7.4.1.1India Biomaterials Market (by Application and Sub-Application) .................... 202 4.5.7.4.2Product ................................................................................................................... 204 4.5.7.4.2.1India Biomaterials Market (by Product Type and Sub-Product Type) ............ 204 4.5.7.5 Rest-of-Asia-Pacific ........................................................................................ 205 All rights reserved at BIS Research Inc. 13

14. 4.5.7.5.1Application .............................................................................................................. 206 4.5.7.5.1.1Rest-of-Asia-Pacific Biomaterials Market (by Application and Sub- Application) ............................................................................................................ 206 4.5.7.5.2Product ................................................................................................................... 207 4.5.7.5.2.1Rest-of-Asia-Pacific Biomaterials Market (by Product Type and Sub- Product Type) ........................................................................................................ 207 4.6 Rest-of-the-World .......................................................................................... 211 4.6.1Market ......................................................................................................... 211 4.6.1.1 Key Manufacturers and Suppliers in Rest-of-the-World .................................. 211 4.6.1.2 Business Drivers ............................................................................................ 211 4.6.1.3 Business Challenges ...................................................................................... 211 4.6.2Applications ............................................................................................... 211 4.6.2.1 Rest-of-the-World Biomaterials Market (by Application and Sub- Application), Value and Volume Data ............................................................. 211 4.6.3Product ....................................................................................................... 214 4.6.3.1 Rest-of-the-World Biomaterials Market (by Product Type and Sub-Product Type), Value and Volume Data ...................................................................... 214 4.6.3.2 South America................................................................................................ 216 4.6.4Market ......................................................................................................... 216 4.6.4.1 Buyer Attributes .............................................................................................. 216 4.6.4.2 Key Manufacturers and Suppliers in South America ....................................... 216 4.6.4.3 Business Challenges ...................................................................................... 216 4.6.4.4 Business Drivers ............................................................................................ 216 4.6.4.4.1Application .............................................................................................................. 217 4.6.4.4.1.1South America Biomaterials Market (by Application and Sub-Application) ........................................................................................................................ 217 4.6.4.4.2Product ................................................................................................................... 219 Global Biomaterials Market 4.6.4.4.2.1South America Biomaterials Market (by Product Type and Sub-Product Type) ..................................................................................................................... 219 4.6.4.5 Middle East and Africa ................................................................................... 220 4.6.5Market ......................................................................................................... 220 4.6.5.1 Buyer Attributes .............................................................................................. 220 All rights reserved at BIS Research Inc. 14

15. 4.6.5.2 Key Manufacturers and Suppliers in Middle East and Africa........................... 221 4.6.5.3 Business Challenges ...................................................................................... 221 4.6.5.4 Business Drivers ............................................................................................ 221 4.6.5.4.1Application .............................................................................................................. 221 4.6.5.4.1.1Middle East and Africa Biomaterials Market (by Application and Sub- Application) ............................................................................................................ 221 4.6.5.4.2Product ................................................................................................................... 223 4.6.5.4.2.1Middle East and Africa Biomaterials Market (by Product Type and Sub- Product Type) ........................................................................................................ 223 5 Markets - Competitive Benchmarking & Company Profiles ....... 225 5.1 Competitive Benchmarking .......................................................................... 226 5.2 Company Profiles .......................................................................................... 228 5.2.1BASF SE ..................................................................................................... 228 5.2.1.1 Company Overview ........................................................................................ 228 5.2.1.2 Product Portfolio ............................................................................................. 228 5.2.1.3 Corporate Strategies ...................................................................................... 229 5.2.1.4 Production Sites and R&D Analysis ................................................................ 229 5.2.1.5 Strengths of the Company in the Global Biomaterials Market ......................... 230 5.2.1.6 Weakness of the Company in the Global Biomaterials Market ....................... 230 5.2.2Carpenter Technology Corporation ......................................................... 231 5.2.2.1 Company Overview ........................................................................................ 231 5.2.2.2 Product Portfolio ............................................................................................. 231 5.2.2.3 Corporate Strategies ...................................................................................... 231 5.2.2.4 Production Sites and R&D Analysis ................................................................ 232 5.2.2.5 Strengths of the Company in the Global Biomaterials Market ......................... 232 5.2.2.6 Weaknesses of the Company in the Global Biomaterials Market .................... 232 Global Biomaterials Market 5.2.3Celanese Corporation ............................................................................... 233 5.2.3.1 Company Overview ........................................................................................ 233 5.2.3.2 Product Portfolio ............................................................................................. 233 5.2.3.3 Corporate Strategies ...................................................................................... 234 5.2.3.4 Production Sites and R&D Analysis ................................................................ 234 All rights reserved at BIS Research Inc. 15

16. 5.2.3.5 Strengths of the Company in the Global Biomaterials Market ......................... 235 5.2.3.6 Weaknesses of the Company in the Global Biomaterials Market .................... 235 5.2.4Collagen Solutions Plc .............................................................................. 236 5.2.4.1 Company Overview ........................................................................................ 236 5.2.4.2 Product Portfolio ............................................................................................. 236 5.2.4.3 Corporate Strategies ...................................................................................... 237 5.2.4.4 Strengths of the Company in the Global Biomaterials Market ......................... 237 5.2.4.5 Weakness of the Company in the Global Biomaterials Market ....................... 237 5.2.5Corbion N.V. ............................................................................................... 238 5.2.5.1 Company Overview ........................................................................................ 238 5.2.5.2 Product Portfolio ............................................................................................. 238 5.2.5.3 Corporate Strategies ...................................................................................... 239 5.2.5.4 Production Sites and R&D Analysis ................................................................ 239 5.2.5.5 Strengths of the Company in the Global Biomaterials Market ......................... 240 5.2.5.6 Weaknesses of the Company in the Global Biomaterials Market .................... 240 5.2.6Covestro AG .............................................................................................. 241 5.2.6.1 Company Overview ........................................................................................ 241 5.2.6.2 Product Portfolio ............................................................................................. 241 5.2.6.3 Corporate Strategies ...................................................................................... 241 5.2.6.4 Production Sites and R&D Analysis ................................................................ 242 5.2.6.5 Strengths of the Company in the Global Biomaterials Market ......................... 242 5.2.6.6 Weaknesses of the Company in the Global Biomaterials Market .................... 242 5.2.7DSM ............................................................................................................ 243 5.2.7.1 Company Overview ........................................................................................ 243 5.2.7.2 Product Portfolio ............................................................................................. 243 5.2.7.3 Corporate Strategies ...................................................................................... 243 Global Biomaterials Market 5.2.7.4 Production Sites and R&D Analysis ................................................................ 244 5.2.7.5 Strengths of the Company in the Global Biomaterials Market ......................... 244 5.2.7.6 Weaknesses of the Company in the Global Biomaterials Market .................... 244 5.2.8Evonik Industries....................................................................................... 245 All rights reserved at BIS Research Inc. 16

17. 5.2.8.1 Company Overview ........................................................................................ 245 5.2.8.2 Product Portfolio ............................................................................................. 245 5.2.8.3 Corporate Strategies ...................................................................................... 246 5.2.8.4 Production Sites and R&D Analysis ................................................................ 246 5.2.8.5 Strengths of the Company in the Global Biomaterials Market ......................... 247 5.2.8.6 Weakness of the Company in the Global Biomaterials Market ....................... 247 5.2.9Zimmer Biomet .......................................................................................... 248 5.2.9.1 Company Overview ........................................................................................ 248 5.2.9.2 Product Portfolio ............................................................................................. 248 5.2.9.3 Corporate Strategies ...................................................................................... 249 5.2.9.4 Production Sites and R&D Analysis ................................................................ 249 5.2.9.5 Strengths of the Company in the Global Biomaterials Market ......................... 250 5.2.9.6 Weaknesses of the Company in the Global Biomaterials Market .................... 250 5.2.10Wright Medical Group N.V. ....................................................................... 251 5.2.10.1 Company Overview ........................................................................................ 251 5.2.10.2 Product Portfolio ............................................................................................. 251 5.2.10.3 Corporate Strategies ...................................................................................... 252 5.2.10.4 Strength of the Company in the Global Biomaterials Market........................... 252 5.2.10.5 Weakness of the Company in the Global Biomaterials Market ....................... 252 5.2.11Mitsubishi Chemical Holdings Corporation. ........................................... 253 5.2.11.1 Company Overview ........................................................................................ 253 5.2.11.2 Product Portfolio ............................................................................................. 253 5.2.11.3 Corporate Strategies ...................................................................................... 254 5.2.11.4 Production Sites and R&D Analysis ................................................................ 254 5.2.11.5 Strengths of the Company in the Global Biomaterials Market ......................... 255 5.2.11.6 Weaknesses of the Company in the Global Biomaterials Market .................... 255 Global Biomaterials Market 5.2.12Riton Biomaterial Co., Ltd. ....................................................................... 256 5.2.12.1 Company Overview ........................................................................................ 256 5.2.12.2 Product Portfolio ............................................................................................. 256 5.2.12.3 Strength of the Company in the Global Biomaterials Market........................... 256 All rights reserved at BIS Research Inc. 17

18. 5.2.12.4 Weakness of the Company in the Global Biomaterials Market ....................... 256 5.2.13Berkeley Advanced Biomaterials Inc. ...................................................... 257 5.2.13.1 Company Overview ........................................................................................ 257 5.2.13.2 Product Portfolio ............................................................................................. 257 5.2.13.3 Strength of the Company in the Global Biomaterials Market........................... 257 5.2.13.4 Weakness of the Company in the Global Biomaterials Market ....................... 257 5.2.14BBS-Bioactive Bone Substitutes Oyj ....................................................... 258 5.2.14.1 Company Overview ........................................................................................ 258 5.2.14.2 Product Portfolio ............................................................................................. 258 5.2.14.3 Corporate Strategies ...................................................................................... 259 5.2.14.4 Strength of the Company in the Global Biomaterials Market........................... 259 5.2.14.5 Weakness of the Company in the Global Biomaterials Market ....................... 259 5.2.15Bioretec Ltd. .............................................................................................. 260 5.2.15.1 Company Overview ........................................................................................ 260 5.2.15.2 Product Portfolio ............................................................................................. 260 5.2.15.3 Corporate Strategies ...................................................................................... 260 5.2.15.4 Strength of the Company in the Global Biomaterials Market........................... 260 5.2.15.5 Weakness of the Company in the Global Biomaterials Market ....................... 260 6 Research Methodology ........................................................... 261 Global Biomaterials Market All rights reserved at BIS Research Inc. 18

19. List of Figures Figure 1: Global Biomaterials Market Snapshot, 2020, 2021 and 2031 Figure 2: Global Biomaterials Market (by Product Type) Figure 3: Global Biomaterials Market (by Region), $Billion, 2021 and 2031 Figure 4: Global Biomaterials Market: Coverage Figure 5: Supply Chain Analysis of Global Biomaterials Market Figure 6: Porter’s Five Forces Analysis Figure 7: Year-Wise Patents Filed in Global Biomaterials Market, January 2018-August 2021 Figure 8: Patent Analysis (by Status), January 2018-August 2021 Figure 9: Patent Analysis (by Organization), January 2018-August 2021 Figure 10: Market Dynamics: Global Biomaterials Market Figure 11: Number of Plastic Surgery Procedures (by Country), 2019 Figure 12: Leading Causes of Deaths by American Heart Association Figure 13: Total Developments of Biomaterials (2018-2021) Figure 14: Competitive Benchmarking Matrix Figure 15: R&D Expenditure of BASF SE, 2019-2020 Figure 16: R&D Expenditure of Carpenter Technology Corporation, 2018-2020 Figure 17: R&D Expenditure of Celanese Corporation, 2018-2020 Figure 18: R&D Expenditure of Corbion N.V., 2019-2020 Figure 19: R&D Expenditure of Covestro AG, 2019-2020 Figure 20: R&D Expenditure of DSM, 2019-2020 Figure 21: R&D Expenditure of Evonik Industries, 2018-2020 Figure 22: R&D Expenditure of Zimmer Biomet, 2019-2020 Figure 23: R&D Expenditure of Mitsubishi Chemical Holdings Corporation, 2019-2020 Figure 24: Research Methodology Figure 25: Top-Down and Bottom-Up Approach Figure 26: Assumptions and Limitations Global Biomaterials Market All rights reserved at BIS Research Inc. 19

20. List of Tables Table 1: Global Biomaterials Market (by Application) Table 2: Key Factor in Determining “Threat of New Entrants” in Biomaterials Market Table 3: Key Factor in Determining “Bargaining Power of Buyers” in Biomaterials Market Table 4: Key Factor in Determining “Bargaining Power of Suppliers” in Biomaterials Market Table 5: Key Factor in Determining “Threat of Substitutes” in Biomaterials Market Table 6: Key Factor in Determining “Intensity of Competitive Rivalry” in Biomaterials Market Table 7: Impact Analysis of Driver Table 8: Global Aging Population Table 9: Impact Analysis of Restraint Table 10: Impact Analysis of Opportunity Table 11: Key Product Launch and Development Activities (2018-2021) Table 12: Key Partnerships, Collaborations, and Contracts (2018-2021) Table 13: Key Business Expansion Activities (2018-2021) Table 14: Key Mergers, Acquisitions, and Joint Ventures (2018-2021) Table 15: Other Key Developments (2018-2021) Table 16: Global Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 17: Global Biomaterials Market (by Application), Kilo Ton, 2020 -2031 Table 18: Global Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 19: Global Biomaterials Market (by Product Type), Kilo Ton, 2020-2031 Table 20: North America Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 21: North America Biomaterials Market (by Application), Kilo Ton, 2020-2031 Table 22: North America Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020- 2031 Table 23: North America Biomaterials Market (by Product Type), Kilo Ton, 2020-2031 Table 24: U.S. Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 25: U.S. Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 26: Canada Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Global Biomaterials Market Table 27: Canada Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 28: Mexico Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 29: Mexico Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 30: Europe Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 All rights reserved at BIS Research Inc. 20

21. Table 31: Europe Biomaterials Market (by Application), Kilo Ton, 2020-2031 Table 32: Europe Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 33: Europe Biomaterials Market (by Product Type), Kilo Ton, 2020-2031 Table 34: Germany Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 35: Germany Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 36: France Biomaterials Market (by Application and Sub-application), $Billion, 2020-2031 Table 37: France Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 38: Spain Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 39: Spain Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 40: Italy Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 41: Italy Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 42: Russia Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 43: Russia Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 44: Rest-of-Europe Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 45: Rest-of-Europe Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020- 2031 Table 46: U.K. Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 47: U.K. Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 48: China Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 49: China Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 50: Asia-Pacific & Japan Biomaterials Market (by Application and Sub-Application), $Billion, 2020- 2031 Table 51: Asia-Pacific & Japan Biomaterials Market (by Application), Kilo Ton, 2020-2031 Table 52: Asia-Pacific & Japan Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 53: Asia-Pacific & Japan Biomaterials Market (by Product Type), Kilo Ton, 2020-2031 Table 54: Japan Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 55: Japan Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 56: South Korea Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Global Biomaterials Market Table 57: South Korea Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020- 2031 Table 58: India Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 59: India Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 All rights reserved at BIS Research Inc. 21

22. Table 60: Rest-of-Asia-Pacific Biomaterials Market (by Application and Sub-Application), $Billion, 2020- 2031 Table 61: Rest-of-Asia-Pacific Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 62: Rest-of-the-World Biomaterials Market (by Application and Sub-Application), $Billion, 2020- 2031 Table 63: Rest-of-the-World Biomaterials Market (by Application), Kilo Ton, 2020-2031 Table 64: Rest-of-the-World Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Table 65: Rest-of-the-World Biomaterials Market (by Product Type), Kilo Ton, 2020-2031 Table 66: South America Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 67: South America Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020- 2031 Table 68: Middle East and Africa Biomaterials Market (by Application and Sub-Application), $Billion, 2020-2031 Table 69: Middle East and Africa Biomaterials Market (by Product Type and Sub-Product Type), $Billion, 2020-2031 Global Biomaterials Market All rights reserved at BIS Research Inc. 22

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