Schmidt lab biomaterials applications
Sponsored Links
This presentation is the property of its rightful owner.
1 / 7

Schmidt Lab Biomaterials Applications PowerPoint PPT Presentation


  • 52 Views
  • Uploaded on
  • Presentation posted in: General

Schmidt Lab Biomaterials Applications. Spinal Cord Repair Strategies (Zin). Soft Tissue Scaffolds (Richelle). Surgical Meshes (Sarah). Sources of Peripheral Nerve Injury. Cancer. Accidents. Congenital Defects. Photocrosslinked Hyaluronic Acid (GMHA). High Swelling HA Hydrogels.

Download Presentation

Schmidt Lab Biomaterials Applications

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


Schmidt Lab Biomaterials Applications

Spinal Cord Repair Strategies

(Zin)

Soft Tissue Scaffolds (Richelle)

Surgical Meshes

(Sarah)


Sources of Peripheral Nerve Injury

Cancer

Accidents

Congenital

Defects


Photocrosslinked Hyaluronic Acid(GMHA)

High Swelling HA Hydrogels

Low Swelling HA Films

Unswollen

Saline Swollen

Water Swollen

Modulate:

-Swelling

-Degradation

-Mechanical Properties


25 mm

12 mm

Role of Physical vs. Chemical Cues

Microchannels vs. Laminin

Gomez, Chen, Schmidt (2007). J. R. Soc Interface. 4(13): 223-233.

Physical cues are preferred over

chemical cues for axon initiation (polarization)

70 %  Physical Cues (microchannels)

30 %  Chemical Cues (NGF or Laminin)


In Situ Crystallization:

Dendritic Pores

In Situ Crystallization: Dendritic Pores

  • Simple, inexpensive

  • No specialized equipment

  • No specialized skills

  • No organic solvents


Fibrillar, Porous Microstructure

AFM

SEM


Cell Guidance

Zawko, Schmidt. (in press) Acta Biomaterialia.


  • Login