Schmidt Lab Biomaterials Applications. Spinal Cord Repair Strategies (Zin). Soft Tissue Scaffolds (Richelle). Surgical Meshes (Sarah). Sources of Peripheral Nerve Injury. Cancer. Accidents. Congenital Defects. Photocrosslinked Hyaluronic Acid (GMHA). High Swelling HA Hydrogels.
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Spinal Cord Repair Strategies
Soft Tissue Scaffolds (Richelle)
High Swelling HA Hydrogels
Low Swelling HA Films
Microchannels vs. Laminin
Gomez, Chen, Schmidt (2007). J. R. Soc Interface. 4(13): 223-233.
Physical cues are preferred over
chemical cues for axon initiation (polarization)
70 % Physical Cues (microchannels)
30 % Chemical Cues (NGF or Laminin)
In Situ Crystallization:
In Situ Crystallization: Dendritic Pores
Fibrillar, Porous Microstructure
Zawko, Schmidt. (in press) Acta Biomaterialia.