Cancer What is Cancer? Group of diseases characterized by new cells that divide and grow unrestrained. Johannes Muller discovered that tumors were made up of cells. Neoplasm: “New growth.” Neoplastic growths rob nutrients and provide no benefit to the organism Ovarian Cancer Cell
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Ovarian Cancer Cell
Growth of Tumor
Attachment to endothelium
Transport Interaction with Vascular Components
Invasion through Basement Membrane
Establishment of Micrometastases
Maureen Reagan died of metastatic melanoma (brain and bone involvement) in 2001 at age 60.
Basal Cell Carcinoma
Squamous Cell Carcinoma
7 cents from the sale of each stamp went to fund breast cancer research
Stage A : Deep tumor. May not be detected by digital-rectal exam
Stage B: Tumor may be detected by DRE or ultrasound
Stage D: Metastasis to bone and lymph nodes
Stage C: Spread to surrounding tissue
Glioma, or cancer arising in the glial cells of the brain. Note its position inside a ventricle.
MRI showing no tumor (left) and three months later (right)
Malignant melanoma is a form of skin cancer that can be fatal. Other forms generally don’t contribute to cancer mortality.
1. Multiple partners
2. Low SES
3. Early 1st sexual experience
4. Early pregnancies
5. Male sex partners who have had multiple partners
Living near a nuclear power plant does not increase cancer risk.
1% Cancer Incidence
Shaffer, J.W., Graves, P.L., Swank, R.T., & Pearson, T.A. (1987). Clustering of personality traits in youth and subsequent development of cancer among physicians. Journal of Behavioral Medicine, 10, 441-447.
Loners & Emotional Suppression
16% Cancer Incidence
30 years later
Beginning of Study
1. Access to information
2. Sense of personal control
3. Self Esteem
1. Social support
2. Group therapy with patients who
have the same cancer
3. An educational component
4. Training in coping strategies