OS-120 Brightfield Digital Pathology Scanner

1. Global Leader in Affordable Digital Pathology OptraSCAN® OS-120 Scanner OS-120 is a small footprint, high throughput, cloud-enabled scanners It’s convenient for brightfield scanning and can scan 120 tissue slides at a time. These whole slide scanners provide high-resolution images of digital slides and associated metadata. Key Features TELEPath® Telepathology included for real-time, remote consultations Small footprint, high throughput, whole slide, brightfield scanners with 120 slides capacity User friendly, intuitive LCD touchscreen High resolution imaging of digital slides and associated metadata Cloud-enabled with instant cloudloading capability One-touch walk-away automation Bar code and case reconciliation IMAGEPath® image management system included for viewing, storing & archiving Easy installation OPTRASCAN INC.,CA USA +1 (408) 524-5300 OptraSCAN® is an ISO13485 certified company OptraSCAN® whole slide scanners are CE marked for IVD use OptraSCAN® systems are for research use in North America info@optrascan.com www.optrascan.com @OptraSCAN

2. OptraSCAN® is an ISO 13485 certified company OptraSCAN® systems are CE mark for IVD use OptraSCAN systems are for research use only in North America On-Demand Digital Pathology® Includes Flexible Subscription Options OS-120 Scanner Support Image Management Annual Maintenance & Upgrades Telepathology Software Discounts Affordable Price Technical Specifications OS-120 (SD) Speed: Scans whole slides in < 1 minute at 20x & 3 minutes at 40x Imaging Mode: Brightfield File Format: JPEG2000, software can convert image file formats Image Storage Space: 300MB for a 15x15mm tissue Slide Formats: Standard 25 x 75mm (1”x3”) slides Operating System: Windows 7, 8, 8.1, 10 Dimensions & Weight for OS-120 : Approximate Width- 14”, Length- 17”, Height- 18”, Weight- 88lbs Resolution: 0.50 μm/pixel at 20x, 0.25 μm/pixel at 40x Image capture region: 25x50mm Scanning Capability: 120-slide continuous loading capacity & scanning capability with 8 cartridge carousel IMAGEPath® Web-based Image Management and Viewing • Image sharing, collaboration and storage security • Pan, zoom, annotate, generate reports • User authentication and role-enabled access • Image analysis plug-in available • Audit trail functionality OptraSCAN India Pvt. Ltd. Qubix SEZ, Hinjewadi Phase I Pune, Maharashtra 020-66540900 OptraSCAN Inc. 100 Century Center Court, Suite 410, San Jose, CA 95112, USA, Tel : +1-408-524-5300 info@optrascan.com www.optrascan.com

3. OptraSCAN® is an ISO 13485 certified company OptraSCAN® systems are CE mark for IVD use OptraSCAN systems are for research use only in North America TELEPath® Real-time Digital Conferencing • Real-time sharing/collaboration • Interactive chat • iOS and android based applications OptraASSAYS® Image Analysis AI & ML based Image Analysis Solutions • Turnkey analysis of ER, PR, Her2neu, Ki67, PD-L1 • IHC multiplexing assays • Accurate, rapid & reproducible assessment • Additional algorithms available with user configuration • Biomarker quantification using nuclear, membrane & cytoplasmic stains Nuclear Biomarker Analysis • Identification of optical density vectors • Easily tunable training & classifying modules • Batch processing and single slide analysis • Computer assisted whole slide & regions of interest assessment for quantification of nuclear algorithm Membrane Biomarker Analysis • Highly reproducible and accurate score generation • IHC dual-plex analysis for each biomarker analyzed • User validation through exposed parameters opened for user interaction • Stroke detection algorithm for filtering out the residual/background staining OptraSCAN India Pvt. Ltd. Qubix SEZ, Hinjewadi Phase I Pune, Maharashtra 020-66540900 OptraSCAN Inc. 100 Century Center Court, Suite 410, San Jose, CA 95112, USA, Tel : +1-408-524-5300 info@optrascan.com www.optrascan.com

4. OptraSCAN® is an ISO 13485 certified company OptraSCAN® systems are CE mark for IVD use OptraSCAN systems are for research use only in North America PD-L1 Biomarker Analysis • Fully automated solution for interpretation of PD-L1 IHC expression • Computer aided region detection system based for automated evaluation of tumor nest • Score generation based on the number of PD-L1 positive cells in relation to total tumor and immune cells in a single read Prostate Cancer Analysis • End to end, fully automated solution for prostate cancer • ANN (artificial neural network) based classifier • ML based histological assessment of architectural patterns Cytology Imaging • Fully automated multi-layer scanning at different focal depths • User configurable focal intervals for z stacking • Ideal for rapid on-site evaluation for adequacy of cytology samples (rapid on-site evaluation (rose) • Relatively smaller file size than multiplane images. • Effective and easy navigation for accurate interpretation, sharing and archiving OptraSCAN Inc. 100 Century Center Court, Suite 410, San Jose, CA 95112, USA, Tel : +1-408-524-5300 OptraSCAN India Pvt. Ltd. Qubix SEZ, Hinjewadi Phase I Pune, Maharashtra 020-66540900 @OptraSCAN OptraSCAN India Pvt. Ltd. Qubix SEZ, Hinjewadi Phase I Pune, Maharashtra 020-66540900 OptraSCAN Inc. 100 Century Center Court, Suite 410, San Jose, CA 95112, USA, Tel : +1-408-524-5300 info@optrascan.com www.optrascan.com info@optrascan.com | www.optrascan.com