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Part II: Update of Activities of Biotech Task Force. Bob McCarthy, Roche Molecular Biochemicals Phone: 317-576-7475 Fax: 317-576-7317 e mail: [email protected] Alicia Loffler, Director, Center for Biotechnology, Northwestern University

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Part ii update of activities of biotech task force l.jpg

Part II: Update of Activities of Biotech Task Force

Bob McCarthy, Roche Molecular Biochemicals

Phone: 317-576-7475 Fax: 317-576-7317

e mail: [email protected]

Alicia Loffler, Director, Center for Biotechnology, Northwestern University

Phone: 847-467-1453 Fax: 847-467-2180

e mail: [email protected]


Background l.jpg
Background

  • Charter: Use roadmap tools for evaluating technology in the biotech industry

  • Participants:

    • Pharmaceutical/life science research industry

    • Food industry: providers and packagers

    • Development of substitute technology: plant/crop based renewable resources

  • Goal: hold a international workshop on roadmaps for the biotech industry next year

  • Status: 2 meetings May 27 & September 3

    • May 27 kickoff meeting

    • September 3 meeting:

      • Definition of the problem

      • Preliminary discussions on workshop planning


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Phases of Biotech Roadmap

  • Phases of biotech roadmap

    • Phase 1: Learning: gain experience by addressing a manageable but important problem

    • Phase 2: Applying: expand scope to more difficult problems to assess the tool

    • Phase 3: Exploiting: internalize use

  • Critical issue in Phase 1 is to define manageable problem

    • “The person who controls the definition of the problem controls the solution”

    • “A problem well put is half solved”


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Key Issue to Consider in Defining a Problem(source: Mitroff: Smart Thinking for Crazy Times)

  • Pick the right stakeholders

    • Output must meet needs of critical stakeholders

  • Expand your options

    • Single definition of a problem is not acceptable

  • Phrase the problem correctly

    • Phrase using human or technical variables

  • Expand the problems boundaries

    • Never draw too narrowly, challenge comfort zone

  • Be prepared to manage paradox

    • Never solve problem solely by fragmentation

    • Look at system, interactions of system important


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Systems Thinking Approach: TOC

  • Key assumptions of Theory of Constraints (TOC)

    • Any system has at least one constraint, otherwise it would be generating infinite amount of output

    • “A chain is only as strong as its weakest link”

      • Strengthen the chain be addressing weakest link

    • Constraints dictate the performance of an organization to achieve its goal

    • Once the weak link is strengthened, a new link will show itself


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Differing PerspectivesM. Liebman, Wyeth-Ayerst

  • Technology producer vs consumer need

  • Technology vs financial return

  • Technology vs culture

  • Technology vs regulatory issues

  • local/state/region/national/international


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Technology vs CultureM. Liebman, Wyeth-Ayerst

  • Technology- Can You Do It

  • Culture- Should You Do It

  • Issues (Process/System Considerations)

    • convention

    • (re)education

    • ethics

    • regulatory

    • market need

    • economics

    • production, distribution…

    • funding sources

    • innovation vs replacement

    • time vs money


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Next Steps

  • Divide group into 3 sub-groups

    • Pharmaceuticals/life science research

    • Food industry

    • Plant/crop renewable resources

  • Each group to complete the following assignments

    • Construct a value chain/network for their industry

    • Identify critical issues to address in the roadmap

  • Next meeting to be held in mid-October

    • Goal will be to review sub-group reports

    • Use this information to identify topics for the roadmapping effort


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