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Normal urothelium. Cell layers. Urothelium = all epithelial cells. Superficial/umbrella Intermediate 2 to >10 cells Basal . Normal urothelial mucosa. Mucosa = Urothelium + stroma beneath urothelium deep to muscularis mucosae. Normal urothelial mucosa. Normal urothelial mucosa.

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cell layers

Normal urothelium

Cell layers

Urothelium = all epithelial cells

  • Superficial/umbrella
  • Intermediate
    • 2 to >10 cells
  • Basal
slide2

Normal urothelial mucosa

Mucosa = Urothelium + stroma beneath urothelium deep to muscularis mucosae

slide4

Normal urothelial mucosa

Brunn’s nests

Urothelium

Mucosa

Muscularis mucosae

slide5

Normal urothelial mucosa

Urothelium

Cystitis cystica

Mucosa

Muscularis mucosae

muscularis mucosae
Muscularis mucosae

Urothelium

Lamina propria

Mucosa

Submucosa

Lymphoid nodule

Muscularis propria

muscularis mucosae7
Muscularis mucosae

Distribution of muscularis mucosae (as % of bladders)

Prominent & continuous 3 %

Discontinuous & interrupted 20 %

Scattered & dispersed 71 %

Absent 6 %

Muscularis propria

pathologic staging of bladder tumors
Pathologic staging of bladder tumors

Ta and Tis tumors

T1 tumors

T2 tumors

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