MOLECULAR MARKERS AND ITS APPLICATIONS IN LIVESTOCK IMPROVEMENT. Paras Yadav 1 , Aarti Bhardwaj 3 , Shalini Jain 2 and Hariom Yadav 2 1 Animal Biotechnology Division, National Dairy Research Institute, Karnal-132001, Haryana, India
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ITS APPLICATIONS IN LIVESTOCK IMPROVEMENT
Paras Yadav1, Aarti Bhardwaj3, Shalini Jain2 and Hariom Yadav2
1Animal Biotechnology Division, National Dairy Research Institute,
Karnal-132001, Haryana, India
2College of Applied Education and Health Sciences, Meerut, U.P.
Marker is a piece of DNA molecule that is associated with a certain trait of a organism
Animals are selected based on appearance
Disadvantage: lack of polymorphism
Animals are selected based on biochemical properties
Eg. Hb, AMYLASE, BLOOD GROUPS ETC.
Influenced by environment
It covers less than 10% of genome
Animals are selected based on structural & numerical variations
Eg. Structural and Numerical Variations
Structural- Deletions, Insertions etc.
Numerical- Trisomy, Monosomy, Nullysomy
Disadvantage: low polymorphism
Single locus marker
Properties of Different MM
Application of Molecular Markers
A. Conventional breeding strategies
B. Transgenic breeding strategies
The genetic improvement of animals is a continuous and
complex process. Ever since the domestication of animals
by man, he has always remained busy in improving his
animals. In this pursuit many methods have been developed
and tested. In recent years, the demonstration of genetic
polymorphism at the DNA sequence level has provided a
large number of marker techniques with variety of
applications. This has, in turn, prompted further
consideration for the potential utility of these markers in
animal breeding. However, utilization of marker-based
information for genetic improvement depends on the choice
of an appropriate marker system for a given application.