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insulin-like growth factor binding protein 2, 36kDa

Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.<br>SynonymsIGFBP2; insulin-like growth factor binding protein 2, 36kDa; IBP2; IGF-BP53; insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2;

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insulin-like growth factor binding protein 2, 36kDa

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  1. Igfbp2 insulin-like growth factor binding protein 2, 36kDa BackgroundInhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. SynonymsIGFBP2; insulin-like growth factor binding protein 2, 36kDa; IBP2; IGF-BP53; insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2; Recombinant Proteins Cell & Tissue Lysates Cat.# Product name Source (Host) Species IGFBP2-25H Recombinant Human IGFBP2 protein Human +Inquiry IGFBP2-1388HRecombinant Human IGFBP2 Protein, MYC/DDK-tagged HEK293 Human MYC/DDK +Inquiry IGFBP2-11H Recombinant Human IGFBP2 Yeast IGFBP2-29545TH Recombinant Human IGFBP2 protein Human +Inquiry IGFBP2-477H Recombinant Human IGFBP2, Met-tagged NSO cells Human Met+Inquiry IGFBP2-5049HRecombinant Human Insulin-Like Growth Factor Binding Protein 2, 36kDa High-5 insect cells Human N/A+Inquiry IGFBP2-824H Recombinant Human IGFBP2 protein, His & T7-taggedE. coli Human His/T7 +Inquiry IGFBP2-8072MRecombinant Mouse IGFBP2 Protein Mouse His +Inquiry Igfbp2-825M Recombinant Mouse Igfbp2 protein, His & GST-tagged E. coli Mouse His/GST +Inquiry Igfbp2-969M Recombinant Mouse Igfbp2 Protein, Fc-tagged HEK293 Mouse Fc +Inquiry Igfbp2-970M Recombinant Mouse Igfbp2 Protein, His-tagged Mouse His +Inquiry IGFBP2-3008RRecombinant Rat IGFBP2 Protein Mammalian Cells His +Inquiry Igfbp2-826R Recombinant Rat Igfbp2 protein, His & S-tagged RatHis/S +Inquiry IGFBP2-1188R Recombinant Rhesus IGFBP2 Protein, His-tagged HEK293 Rhesus Macaque His +Inquiry IGFBP2-1414B Recombinant Bovine Insulin-Like Growth Factor Binding Protein 2, 36kDa CHO Bovine N/A+Inquiry IGFBP2-6911C Recombinant Chicken IGFBP2 Mammalian Cells His +Inquiry TagPrice Mammalian cell Human N/A+Inquiry Insect cells Mammalian Cells HEK293 Rat E. coli Chicken

  2. Igfbp2-1749M Recombinant Mouse Insulin-like Growth Factor Binding Protein 2 NS0 Mouse N/A+Inquiry Involved Pathway IGFBP2 involved in several pathways and played different roles in them. We selected most pathways IGFBP2 participated on our site, such as Metabolism of proteins, Myometrial Relaxation and Contraction Pathways, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), which may be useful for your reference. Also, other proteins which involved in the same pathway with IGFBP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway NamePathway Related Protein Metabolism of proteinsNAPB; IGFBP5B;APCS; NAT8; THSD1; OTOP2; DAD1; DHPS; VBP1; ST8SIA2 Myometrial Relaxation and Contraction PathwaysMYLK2; IGFBP2; ACTA1; CNN1; IGFBP4; RGS4; RGS7; RGS11; RGS17; ADM Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)IGFBP6A; PAPPAB; PAPPA2; IGFBP6; IGFBP1A; IGFBP5; IGFBP5A; IGFBP4; IGFBP1B; IGFBP2B Protein Function IGFBP2 has several biochemical functions, for example, insulin-like growth factor I binding, insulin-like growth factor II binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IGFBP2 itself. We selected most functions IGFBP2 had, and list some proteins which have the same functions with IGFBP2. You can find most of the proteins on our site. FunctionRelated Protein Function insulin-like growth factor I bindingRelated Protein IGFBP6A; INSR; IGFBP2B; IGFBP4; IGFBP2A; IGFBP2; IGFBP1B; IGF1R; IGFBP5B; IGFBP5 Function insulin-like growth factor II bindingRelated Protein IGFBP3; IGFBP6A; IGFBP5B; IGFBP6; IGFBP2A; IGFBP1A; IGFBP5; IGFBP6B; INSR; IGFBP2 Function protein bindingRelated Protein NINJ1; EIF3H; ANXA6; NAPG; EFEMP2; RPL14; TAG-260; STAT5A; ST13; FHL3 Interacting Protein IGFBP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGFBP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGFBP2. INO80B; aroP; GSDMB IGFBP2 Related Articles Kang, Z; Yu, Y; et al. Downregulation of IGFBP2 is associated with resistance to IGF1R therapy in rhabdomyosarcoma. ONCOGENE 33:5697-5705(2014).

  3. Strimpakos, A; Pentheroudakis, G; et al. The Prognostic Role of Ephrin A2 and Endothelial Growth Factor Receptor Pathway Mediators in Patients With Advanced Colorectal Cancer Treated With Cetuximab. CLINICAL COLORECTAL CANCER 12:267-274(2013).

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