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Topic 7

Topic 7. Nucleic Acids and Proteins. DNA Structure. DNA Structure cont’d. DNA Replication. Organization of DNA in Eukaryotes. Replication Initiation Sites Where the replication of DNA begins (may also be known as O.O.R.).

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Topic 7

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  1. Topic 7 Nucleic Acids and Proteins

  2. DNA Structure

  3. DNA Structure cont’d

  4. DNA Replication

  5. Organization of DNA in Eukaryotes • Replication Initiation Sites • Where the replication of DNA begins (may also be known as O.O.R.)

  6. Globular structures that contain 8 histone proteins, with DNA wrapped around 2 times Are connected to other nucleosomes by another histone protein (H1), known as a linker Essential for packaging DNA for mitosis/meiosis Involved in gene regulation Nucleosomes

  7. DNA Folding

  8. DNA Folding

  9. Repetitive Sequences • Repetitive base sequences that are not translated • Sometimes called satellite DNA • Sequences between 5-300 bp • May be repeated as much as 10,000x • Constitute 10-40% of euk. genomes • Function unknown • A vey small portion of euk. DNA is single copy/unique genes

  10. Introns and Exons

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