Adipokine The traditional concept is that adipose tissue is an inert tissue that functions as storing fat, supplying energy and insulation, absorbing shock, regulating body temperature, filling and fixing. However, in recent years it has been observed that adipose tissue is also an endocrine organ with active metabolism and complex functions. The factors that are widely affected by the secretion of adipose tissue and regulate the body's energy metabolism are called adipokines. This factor plays an important part in obesity, cardiovascular disease, immunoreaction and blood glucose regulation. However, with the widespread use of this term, its meaning has also been expanded. Current adipocytokines can represent cytokines, acute phase reactants, growth factors, other inflammatory mediators, hormones secreted by adipose tissue (such as leptin), and other chemical messengers.