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Biosafety and Biosecurity in Pakistan

Biosafety and Biosecurity in Pakistan. Yusuf Zafar Chief Scientist/ Director General Biosciences Division Pakistan Atomic Energy Commission (PAEC). FAISALABAD. MAJOR BIOTECHNOLOGY CENTERS. JAMSHORO. Pakistan. 170 Million Population 70% depend on Agriculture. Literacy Rate: 54%

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Biosafety and Biosecurity in Pakistan

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  1. Biosafety and Biosecurity in Pakistan Yusuf Zafar Chief Scientist/ Director GeneralBiosciences DivisionPakistan Atomic Energy Commission (PAEC)


  3. Pakistan 170 Million Population 70% depend on Agriculture Literacy Rate: 54% Universities/Institutes:132 Biotech Institutes: 29

  4. National Biosafety Centre

  5. Scope of Guidelines Laboratory Work Commercial Release of Regulated Materials Field Work i) Repeat the experiments made during laboratory work, and verify the results from tests performed at the laboratory level. ii) Gather precise and accurate information/data on the stability, expression and hereditary transmission of trans genes under field conditions. iii) Assess the viability (e.g. survival, propagation, competitive ability) of genetically manipulated organisms under field conditions. iv) Assess the adaptive or evolutionary potential of genetically manipulated organisms under changing environmental conditions. v) Asses the overall environmental impact.

  6. Four Levels of Biosafety 1: Material not known to consistently cause disease in healthy adults. 2: Associated with human disease. Hazard is from percutaneous injury, ingestion, or mucous membrane exposure. 3: Indigenous or exotic agents with potential for aerosol transmission; disease may have serious or lethal consequences. 4: Dangerous/exotic agents which pose a high risk of life-threatening disease, aerosol-transmitted lab infections or related agents with unknown risk of transmission.

  7. Establishment of National Core Group in Life Sciences (NCGLS) Recognizing the importance of Life Sciences the Higher Education Commission established the Core Group in Life Sciences with six different disciplines. These include • Botany • Genetics • Microbiology • Biochemistry /Molecular Biology • Zoology • Bioinformatics

  8. Aims And Objective • Promotion of teaching and research in Life Sciences in Pakistan. • Identification of areas in Life Sciences which have a direct and major impact on the economy and well being of the country. • Preparation of major projects in these areas. • Human resource development in Life Sciences in Pakistan.

  9. Achievements of NCGLS • More than 3500teachers have been trained in various advanced biological techniques through 55 national and International workshops and conferences. • 4 Resource Centers have been established at various universities.

  10. Life Sciences directoryhaving complete contact information of all life scientists in Pakistan has been published and distributed among the scientists.

  11. Joining of NCGLS with International Council for the Life Science (ICLS) as Associate Member

  12. ICLS meeting in Washington • Curriculum for Biosafety and Biosecurity • NCLS set-up a sub-committee to develop a curriculum

  13. National Commission on Biotechnology Establishment: 30th November 2001 Members: 15 Tasks and Future Initiatives: • Human Resource Development. • Strengthening research facilities in provinces. • Funding young researchers for projects of high priority. • Establishment of centre for Bioinformatics. • To strengthen Government-Private sector collaboration. • Publications, T.V. and Radio Programmes. • Encouraging research which increases export.

  14. Biotechnology Pakistan National Policy and Action Plan 2003 National Commission on Biotechnology

  15. International Biosafety working group recognized Pakistan Biological Safety Association

  16. www.pakbiosafety.com

  17. Dr. Terrence Taylor President International Council for Life Sciences and Vice President of Global Health and Security in Washington DC

  18. First International Seminar on Laboratory Biosafety Issues 21st March 2009

  19. Asia conference on Laboratory Biosafety and Biosecurity Bangkok, Thailand April 17-19, 2007

  20. National Training Seminar on Bio-safety and Bio-security Initiatives June 18-19, 2007,Islamabad

  21. Ministry of Foreign Affairs • Established an inter-agency working group to develop • code of ethics and biosafety law • 20 Stakeholders took part in this meeting • Dr. Anwar Nasim elected convener of the Task Force • 9th June,2009

  22. Ministry of Foreign Affairs Visit of 3-Member Delegaton of US Bio-security Engagement Programme (BEP) 22nd June 2009

  23. Aga Khan University Two Seminars on Laboratory Biosafety March 21, 2009 December 05, 2009 At Aga Khan University,Karachi, PAKISTAN

  24. Biosafety and Biosecurity International Conference Healthier and more secure communities in MENA region 2009 Casablanca, MOROCCO April 2-3, 2009

  25. Bio-safety and Bio-security Risk Assessment and Risk Mitigation Training Event for Pakistani Bio-scientists, 24 Pakistani scientists participated Dubai, United Arab Emirates,12-14 January 2010

  26. Pak-USA BEP Workshop-1 • Cairo 3-6 May,2010 • 12 Project proposals submitted • 27 participants from Pakistan

  27. Pak-USA BEP Workshop-2 • Istanbul, Turkey • 20-23 September,2010 • 3 Projects approved for funding

  28. BEP Approved Projects (03) • Raising awareness of dual use education and Biosecurity issues • Dr Sumi Paranjape US; Dr Zabta Khan QAU, Pak • Survey of clinical labs in Karachi • Dr Sumi Paranjape US; Dr Shamsul Arif, PBSA, Pak • Publication of biosafety manual in Urdu • Dr Sumi Paranjape US; Mr Iqbal Nabi Nadeem, Pak

  29. PAK-US BEP Workshop-3 • Istanbul, Turkey November,2010 • Review 9 projects for funding • Organise future plans

  30. Dual-use Dilemma Dual-use dilemma arises that a piece of scientific research has the potential to be used for harm as well as for good

  31. Dual-use project Quaid-e-Azam University Islamabad

  32. Curriculum Developed for Master’s, Undergraduate & Graduate students of life sciences for biosafety & biosecurity

  33. Two semester class on laboratory biosafety and biosecurity

  34. First Semester Laboratory Biosafety and Biosecurity Fundamentals I

  35. Second Semester Laboratory Biosafety and Biosecurity Fundamentals II

  36. Third Semester Special Topics in Laboratory Biosafety and Biosecurity

  37. Quaid-e-Azam University Course code: Mic-441 Principles of Biosafety Course code: Mic-575 Biological Safety and Risk Management Course code: Mic-442 Risk Management

  38. Course Contents offered at NIBGE Introduction to Biosafety Introduction of laboratory safety, bio-safety procedures, use and disposal of bio-hazardous materials, regulator issues and established guidelines for safe practices

  39. National University of Agricultural Sciences NARC/PARC Bio-safety Environmental Aspects of Gene Technology Overview of biotechnology and bio-safety issues concerns, international treaties/agreements in bio-safety, principles of risk assessment and risk management, factors affecting biodiversity…….

  40. Department of Microbiology University of Karachi Biosafety and Biosecurity Lab risks and assessment, principle of biosafety and safe lab practices, spills and emergencies, risk groups and classification of infectious agents, infectious material, lab biosecurity levels P1,P2,P3 and P4, collection, packaging, transportation and disposal of infections material……

  41. Pakistan Medical Research Council National Bioethics Committee (NBC) 1. Research Ethics Committee 2. Medical Ethics Committee NBC is an advisory body which deals with all aspects of bioethics in the health sector www.pmrc.gov.pk

  42. Education and networking projects on dual use and biosecurity. Giulio Mancini, ITALY James Revill, University of BRADFORD Anwar Nasim, PAKISTAN Zabta Khan Shinwari, PAKISTAN Khalid RiffiTemsamani, MOROCCO

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