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This study examines the impact of Cox-2fl/fl deletion on skin tumor development in a mouse model with DMBA/TPA treatment. Analysis of skin papilloma formation post-TPA treatment reveals significant findings. Refer to Supplemental Figure S5 for detailed results.
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A B C D Cox-2fl/fl Untreated skin 1xTPA skin SkinPapilloma Same mouse (DMBA/TPA) Supplemental Figure S5