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How viruses are important in Biotechnology.<br>Beneficial uses of Viruses.<br>Gene Therapy Tools.<br>Tumour Targeting Virus. <br>Direct Use in Vaccines.
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Importance of viruses in BiotechnologyBy ZAINAB TAHIR
Beneficial uses of viruses in Biotechnology Gene therapy Vaccines and vaccine carrier / delivery vehicles Antibacterial agents Basic knowledge of cell metabolic processes Vectors for mammalian, plant and insect cell protein expression systems Peptide display industrial /pharmaceutical / medical reagent development
Design of virus based Nano-material Virus-based nanomaterial are versatile materials that naturally self-assemble and have relevance for a broad range of applications including medicine, biotechnology and energy.
Direct use in vaccines Against autologous virus Against heterologous virus
Tumour Targeting Viruses Not only does the virus directly infect and kill cancer cells, but it also profoundly alters the tumour microenvironment, making the tumour more visible to the immune system and increasing its vulnerability to immune-oncology therapies.
Viruses in materials world . Most viruses are made up of coat protein subunits that naturally self-assemble. With more understanding of the coat protein building blocks and chemical biology, ever increasing complex assemblies can be programmed, including Nano boomerang- and tetrapod-shaped virus materials. Large-scale production of viruses can be easily achieved through propagation in their natural hosts or expression in a heterologous system.
Gene Therapy Tools RNA viruses have been subjected to substantial engineering efforts to support gene therapy applications and vaccine development Typically, retroviruses, lentiviruses, alphaviruses, measles viruses, Newcastle disease viruses and picornaviruses have been employed as expression vectors for treatment of various diseases including different types of cancers, haemophilia, vaccination with viral vectors has evaluated immunogenicity against infectious agents and protection against challenges with pathogenic organisms.