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Laboratory animals welfare issues : a scientific and legislative perspective. Gianpaolo Milite DVM, M.Sc Moscow , October 17th 2012. Driven by a concept .

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laboratory animals welfare issues a scientific and legislative perspective

Laboratoryanimals welfare issues: a scientific and legislative perspective

Gianpaolo Milite

DVM, M.Sc

Moscow, October 17th 2012

driven by a concept
Drivenby a concept.

“Animal welfare is a valueof the Unionthat is enshrined in Article 13 ofTreaty on the Functioningof the EuropeanUnion (TFEU)”

Directive 2010/63/EU of the EuropeanParliament and of the Councilof 22 september 2010 on the protectionofanimalsusedforscientificpurposes. Art 2.

a long way to change and improve
A long way to change and improve…

Directive 63/2010 UE

Directive 86/609/CEE

In 2007 Recommendations

from the EU Commission

24 yearssince the first Directive and the last 11 dedicated to develop the newDirective.

few numbers
Fewnumbers……

Directive 86/609/CEE

27 articles

22 pages

2 Annex

Directive 63/2010 UE

66 articles

47 pages

8 Annex

56 Introductorystatements…..

slide6

Directive2010/63/UE

  • Mouse (Musmusculus)
  • Rat(Rattusnorvegicus)
  • Guinea Pig (Cavia porcellus)
  • Golden Hamster(Mesocricetusauratus)
  • ChineseHamster(Cricetulusgriseus)
  • MongolianGerbil(Merionesunguiculatus)
  • Rabbit(Oryctolaguscuniculus)
  • Dog (Canisfamiliaris)
  • Cat(Feliscatus)
  • All non humanprimates
  • Frogs[Xenopus (laevis, tropicalis), Rana (temporaria, pipiens)]
  • Zebra Fish(Daniorerio)
an important point
An importantpoint.
  • In AnnexVI

Listofpoints to bementioned in anyexperimentalprotocol:

……..

10. Housing, husbandry and care conditions for the animals.

……...

the scientific issue of welfare
The scientificissueof welfare
  • Is a matterof performance standard of the equipment.
  • In otherwordsitmeans: the studyofany impact due to the housing environment on animal welfare
welfare indicators
Welfare indicators
  • appearance,
  • body weight,
  • coat condition,
  • posture,
  • gait,
  • activity levels,
  • interaction with the environment and clinical signs,
  • feeding behaviour,
  • drinking behaviour,
  • defecation,
  • Urination,
  • cortisole,
  • breeding performances….
slide17

TIZ-BIFO European

Guidelines on IVCs

conclusions
Conclusions
  • The newEuropeanLegislation is focusing on animal welfare at 360 degree, directly (animal housing, environment etc.) and indirectlythrough the requestforspecializeddedicated staff.
  • The onlyapparentlimitedchanges in the newlegislationrepresents a revolution in the approach to animal experiment.