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氰化物中毒解救机理
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氰化物中毒解救机理. 氰化物中毒解救机理. 目前一般采用氧化剂 ( 如亚硝酸钠、大剂量的亚甲蓝等 ) 结合供硫剂 ( 硫代硫酸钠 ) 联合解毒。氧化剂使部分低铁血红蛋白氧化为高铁血红蛋白,高铁血红蛋白中的 Fe3+ 与 CN— 有很强的结合力,不但能与血液中游离的氰离子结合,形成氰化高铁血红蛋白,使氰离子不能产生毒性外,还能夺取已与细胞色素氧化酶结合的氰离子,使细胞色素氧化酶复活而发挥解毒作用。. 氰化物中毒解救机理. 亚硝酸钠. CN - / 氰化细胞色素氧化酶. MHb. Hb. 细胞色素氧化酶(复活). 氰化高铁血红蛋白.
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氰化物中毒解救机理
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