CNS – Antiepileptic Drugs. Compare and contrast the terms seizure, convulsion and epilepsy. Discuss the indications for antiepileptic therapy (AED). Compare and contrast the first line drugs of choice for AED.
Terms overlap and are used interchangeably to achieve the goal of maintaining a reasonable quality of life.
1. Increase threshold of activity in the motor cortex
Makes it more difficult to excite; reduces response
2. Depress the seizure discharge from its origin
Suppress transmission of impulsesfrom one nerve to the next
3. Decrease the speed of nerve impulse conduction within a given neuron
clorazepate (Tranxene), lorazepam (Ativan)
to go to the bathroom.