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Dent 356-11 Laboratory Session 3: Miscellaneous Disorders of Oral Mucosa

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Dent 356-11 Laboratory Session 3: Miscellaneous Disorders of Oral Mucosa

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    1. Dent 356-11 Laboratory Session 3: Miscellaneous Disorders of Oral Mucosa Dr. Huda Hammad

    2. Lingual Tonsil, Foliate Papillitis Lingual tonsillar tissue located on posterior part of lateral aspect of tongue, with overlying vertical folds known as foliate papillae.

    3. Lingual Tonsil, Foliate Papillitis Foliate papillitis. Oral lymphoepithelial cyst.

    4. Lingual Tonsil, Foliate Papillitis Occasional accessory oral tonsils are found elsewhere in the oral cavity.

    5. Geographic Tongue (Benign Migratory Glossitis) Frequently associated with fissured tongue.

    6. Geographic Tongue (Benign Migratory Glossitis)

    7. Geographic Tongue (Benign Migratory Glossitis) Histopathologic features: - acanthosis at edges. - dense neutrophil infiltration of epithelium (microabscesses) & lamina propria, with underlying chronic inflammation.

    8. Orofacial Granulomatosis

    9. Orofacial Granulomatosis Histopathologically: non-caseating chronic granulomatous inflammation with or without giant cells, and edema of tissue.

    10. Crohn’s Disease

    11. Sarcoidosis Parotid involvement

    12. Sarcoidosis Small non-caseating granulomas consisting of macrophages & epithelioid histiocytes, often with Langhans-type giant cells.

    13. Progressive Systemic Sclerosis (Scleroderma)

    14. Verruciform Xanthoma

    15. Verruciform Xanthoma Histopathologic features: - hyperplastic epithelium with papillary projections. - CT papillae infiltrated by lipid-containing foam cells (xanthoma cells).

    16. Oral Submucous Fibrosis

    17. Amyloidosis

    18. Amyloidosis Positive staining with Congo red, with apple-green birefringence with polarizd light microscopy

    19. Oral Pigmentation: I. Exogenous Pigmentation Superficial staining of mucosa Black hairy tongue

    20. Oral Pigmentation: I. Exogenous Pigmentation Foreign bodies: amalgam tattoo

    21. Oral Pigmentation: II. Endogenous Melanin Pigmentation Developmental causes: - racial pigmentation - Peutz-Jeghers syndrome

    22. Oral Pigmentation: II. Endogenous Melanin Pigmentation Acquired causes: - Addison’s disease, - pulmonary disease

    23. Oral Pigmentation: II. Endogenous Melanin Pigmentation Acquired causes: smoker’s melanosis* Irregularly shaped brownish macular pigmentations of oral tissue that are associated with prolonged tobacco smoking. Maxillary and mandibular anterior labial gingiva, bucccal mucosa, floor of mouth and soft palate. Improvement within months to years of cessation of smoking.

    24. Oral Pigmentation: II. Endogenous Melanin Pigmentation Acquired causes: - idiopathic oral melanotic macule (oral freckle) Melanin incontinence in lamina propria Increased melanin in basal cell layer

    25. Oral Pigmentation: II. Endogenous melanin pigmentation Neoplastic causes: melanoma

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