glucose tolerance test diabetes mellitus l.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
Glucose Tolerance Test Diabetes Mellitus PowerPoint Presentation
Download Presentation
Glucose Tolerance Test Diabetes Mellitus

Loading in 2 Seconds...

play fullscreen
1 / 15

Glucose Tolerance Test Diabetes Mellitus - PowerPoint PPT Presentation


  • 147 Views
  • Uploaded on

Glucose Tolerance Test Diabetes Mellitus. Dr. David Gee FCSN 442 - Nutrition Assessment Laboratory. Prevalence 2006. 20.8 million Americans 7% population 9.6% adults over 20 years 21% adults over 60 years 30% undiagnosed 6.2 million undiagnosed 41 million with ‘pre-diabetes’.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Glucose Tolerance Test Diabetes Mellitus' - yaholo


Download Now An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
glucose tolerance test diabetes mellitus

Glucose Tolerance TestDiabetes Mellitus

Dr. David Gee

FCSN 442 - Nutrition Assessment Laboratory

prevalence 2006
Prevalence2006
  • 20.8 million Americans
    • 7% population
      • 9.6% adults over 20 years
      • 21% adults over 60 years
  • 30% undiagnosed
    • 6.2 million undiagnosed
  • 41 million with ‘pre-diabetes’
implications of the diabetes control and complications trial diabetes care 25 s25 s27 2002
Implications of the Diabetes Control and Complications TrialDiabetes Care 25:S25-S27, 2002
  • Conventional Treatment vs Intensive Treatment
    • IT had lower HA1C and FBG
  • Average 7 year follow up
  • Measured outcomes:
    • Retinopathy, nephropathy, neuropathy
  • Results:
    • 60% reduction in risk in intensive treatment group
report of the expert committee on the diagnosis and classification of diabetes mellitus

Report of the Expert Committee on the Diagnosis and Classification ofDiabetes Mellitus

Diabetes Care 28:S4-S36, 2005

See at

Diabetes.org

For health professionals

2005 clinical practice recommendations

criteria for testing for dm in assymptomatic undiagnosed patients
Criteria for testing for DM in assymptomatic, undiagnosed patients
  • > 45 yrs, every 3 yrs (if normal)
  • < 45 yrs, every 3 yrs if:
    • BMI > 25 and any of the following
      • 1st degree relative with DM
      • Blacks, Hispanic, Native American, Asian American
      • Habitually inactive
      • Hx Gestational Diabetes or baby > 9 lbs
      • History of vascular disease
criteria for testing for dm in assymptomatic undiagnosed patients7
Criteria for testing for DM in assymptomatic, undiagnosed patients
  • < 45 yrs, every 3 yrs if: (cont.)
    • Hypertension (>140/90)
    • HDL < 35 mg/dl
    • TG > 250 mg/dl
    • previous Dx of impaired glucose tolerance or impaired fasting glucose
testing of children for type 2 diabetes
Testing of children for Type 2 Diabetes
  • Criteria
    • Overweight (BMI >85th percentile for age and sex, weight for height >85th percentile, or weight >120% of ideal for height)
    • Plus any two of the following risk factors
      • Family history of Type 2 DM, 1o or 2o
      • Native American, black, asian, latino
      • Signs of insulin resistance (acanthosis nigricans, hypertension, dyslipidemia)
    • Age of initiation: 10 yrs or onset of puberty
    • Frequency – every two years
    • Test: FBG test preferred
fasting blood glucose
Fasting Blood Glucose
  • > 8 hr fast
  • DM if FBG > 126 mg/dl (7.0mM)
    • on 2 occasions
  • Pre-Diabetes
    • Impaired fasting glucose (IFG)
    • if : 110 - 125 mg/dl
casual plasma glucose
Casual Plasma Glucose
  • Casual is defined as any time of day without regard to time since last meal
  • > 200 mg/dl (11.1mM) plus
    • Symptoms of diabetes
      • Polyuria, polydipsea, unexplained weight loss
  • Confirm on subsequent visit with fasting blood glucose or oral glucose tolerance test
glucose tolerance testing
Glucose Tolerance Testing
  • for
    • adults with impaired FBG
    • during pregnancy if at risk
  • Procedure
    • Following 8 hour fast
    • Glucose dose = 1.75g/kg IBW
      • Maximum 75 g dose (BW<43kg, 94lbs)
      • 25 g/dl glucose test solution
      • Test at 2 hours
diagnostic criteria
Diagnostic Criteria
  • DM if [glu] > 200 mg/dl at 2 hours
  • IGT if [glu] >140 - 199 at 2 hours
  • normal if [glu] < 140 mg/dl
  • IGT and IFT recently termed “pre-diabetic”
hemoglobin a1c glycated hemoglobin
Hemoglobin A1cglycated hemoglobin
  • Average lifespan of red blood cells
    • ~ 120 days (4 months)
  • Glycosylation of blood proteins in proportion to blood glucose concentration
    • Normal: 5%
    • Goal for diabetics: < 7%